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Mashup Score: 6
The autologous cellular therapy exagamglogene autotemcel is generated by editing an erythroid-specific enhancer of BCL11A. Could another site be edited unintentionally? This study gauged the likeli…
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0FFR-Guided Complete PCI for STEMI | NEJM - 9 hour(s) ago
Quick Take Video Summary from The New England Journal of Medicine — FFR-Guided Complete PCI for STEMI
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Mashup Score: 29
Subcutaneous administration of the monoclonal antibody L9LS protected adults against controlled Plasmodium falciparum infection in a phase 1 trial. Whether a monoclonal antibody administered subcut…
Source: www.nejm.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 0Small-Bowel Bleeding | NEJM - 11 hour(s) ago
Abdominal pain and large-volume hematochezia developed in a man who was in the hospital for a ruptured cerebral aneurysm. Findings on endoscopy and colonoscopy were unremarkable, so CT angiography …
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Mashup Score: 191
Subcutaneous administration of the monoclonal antibody L9LS protected adults against controlled Plasmodium falciparum infection in a phase 1 trial. Whether a monoclonal antibody administered subcut…
Source: www.nejm.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 380Wearable Digital Health Technologies for Monitoring in Cardiovascular Medicine | NEJM - 13 hour(s) ago
Review Article from The New England Journal of Medicine — Wearable Digital Health Technologies for Monitoring in Cardiovascular Medicine
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Mashup Score: 209
Exagamglogene autotemcel (exa-cel) is a nonviral cell therapy designed to reactivate fetal hemoglobin synthesis through ex vivo clustered regularly interspaced short palindromic repeats (CRISPR)–Ca…
Source: www.nejm.orgCategories: General Medicine News, General Journals & SocietTweet-
Of 35 patients with transfusion-dependent β-thalassemia treated with gene-edited autologous hematopoietic stem and progenitor cells, 32 had hemoglobin levels maintained without red-cell transfusions for at least 12 consecutive months. Full study results: https://t.co/LiTmJPoyfq https://t.co/KqsJLFrQJG
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Mashup Score: 10Acute Promyelocytic Leukemia | NEJM - 16 hour(s) ago
A 47-year-old man presented with 2-day history of weakness and fever. Laboratory studies showed pancytopenia. A bone marrow biopsy showed promyelocytes with abundant intracellular rods.
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Mashup Score: 25
Most moderate-to-late–preterm infants need nutritional support until they are feeding exclusively on their mother’s breast milk. Evidence to guide nutrition strategies for these infants is lacking….
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Mashup Score: 144Empagliflozin after Acute Myocardial Infarction | NEJM - 1 day(s) ago
SGLT2 inhibitors improve cardiovascular outcomes in high-risk patients with diabetes, chronic kidney disease, or heart failure, but their effects after acute…
Source: www.youtube.comCategories: General Medicine News, General HCPsTweet
The autologous cellular therapy exagamglogene autotemcel is generated by editing an erythroid-specific enhancer of BCL11A. Could another site be edited unintentionally? This study gauged the likelihood of off-target editing. Read the full correspondence: https://t.co/jX714YVL3A https://t.co/NT58JhlbOM