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Mashup Score: 0Study Classifies Pediatric Radiation Therapy Adverse Effects Into Symptom Profiles - Oncology Nurse Advisor - 22 day(s) ago
The most common symptoms children with cancer experience when undergoing RT were identified, with prevalence by subgroup according to latent profile analysis.
Source: www.oncologynurseadvisor.comCategories: General Medicine NewsTweet
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Mashup Score: 47
PURPOSETo test whether dose-escalated single fraction (SF) stereotactic body radiotherapy (SBRT) of 20 Gy to painful bone metastases is superior to conventional SF three-dimensional (3D) conformal radiotherapy (RT) to a standard dose of 8 Gy in achieving …
Source: ascopubs.orgCategories: General Medicine NewsTweet-
RT @_ShankarSiva: 🚀 New in @JCO_ASCO - ROBOMET https://t.co/ivEq84AP4k! SABR vs standard #radiotherapy for painful bone mets. ✅ Pain relie…
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Mashup Score: 40
PURPOSETo test whether dose-escalated single fraction (SF) stereotactic body radiotherapy (SBRT) of 20 Gy to painful bone metastases is superior to conventional SF three-dimensional (3D) conformal radiotherapy (RT) to a standard dose of 8 Gy in achieving …
Source: ascopubs.orgCategories: General Medicine NewsTweet-
RT @_ShankarSiva: 🚀 New in @JCO_ASCO - ROBOMET https://t.co/ivEq84AP4k! SABR vs standard #radiotherapy for painful bone mets. ✅ Pain relie…
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Mashup Score: 38
PURPOSETo test whether dose-escalated single fraction (SF) stereotactic body radiotherapy (SBRT) of 20 Gy to painful bone metastases is superior to conventional SF three-dimensional (3D) conformal radiotherapy (RT) to a standard dose of 8 Gy in achieving …
Source: ascopubs.orgCategories: General Medicine NewsTweet-
RT @_ShankarSiva: 🚀 New in @JCO_ASCO - ROBOMET https://t.co/ivEq84AP4k! SABR vs standard #radiotherapy for painful bone mets. ✅ Pain relie…
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Mashup Score: 12Defective homologous recombination and genomic instability predict increased responsiveness to carbon ion radiotherapy in pancreatic cancer - 5 month(s) ago
npj Precision Oncology – Defective homologous recombination and genomic instability predict increased responsiveness to carbon ion radiotherapy in pancreatic cancer
Source: www.nature.comCategories: General Medicine News, Hem/OncsTweet-
📢Homologous recombination deficiency (HRD) in pancreatic cancer cells is associated with increased sensitivity to carbon ion #radiotherapy ⚠️ @TedHong9 @StevenLin_MDPhD @xrtGenomics @sophia_kamran @JanPOSchuemann https://t.co/GEJ1abgIzS
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Mashup Score: 12Modeling the acute mucosal toxicity to fractionated radiotherapy combined with the ATM inhibitor WSD0628 - 7 month(s) ago
Abstract. ATM inhibitors are being developed as radiosensitizers to improve the antitumor effects of radiotherapy, but ATM inhibition can also radiosensitize normal tissues. Therefore, understanding the elevated risk for normal tissue toxicities is critical for radiosensitizer development. This study focused on modeling the relationship between acute mucosal toxicity, radiation dose, fractionation schedule, and radiosensitizer exposure. The ATM inhibitor WSD0628 was combined with single or fractionated doses of radiation delivered to the oral cavity or esophagus of FVB mice. The potentiation by WSD0628 was quantified by a sensitizer enhancement ratio (SER), which describes the changes in radiation tolerance for radiation combined with WSD0628 relative to radiation-only regimens. WSD0628 profoundly enhanced radiation-induced acute oral and esophageal toxicities. For oral mucosal toxicity, the enhancement by WSD0628 with 3 fractions of radiation resulted in an SER ranging from 1.3 (0.25
Source: aacrjournals.orgCategories: General Medicine News, Hem/OncsTweet-
Nicely done mouse study by @MayoRadOnc on the radiobiology of combining a DDR inhibitor with #radiotherapy👍 @mct_aacr @DKirschMDPhD @xrtGenomics Modeling the acute mucosal toxicity to fractionated radiotherapy combined with the ATM inhibitor WSD0628 https://t.co/EdfNpDVZKV
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Mashup Score: 32
PURPOSENRG-RTOG0617 demonstrated a detrimental effect of uniform high-dose radiation in stage III non–small cell lung cancer. NRG-RTOG1106/ECOG-ACRIN6697 (ClinicalTrials.gov identifier: NCT01507428), a randomized phase II trial, studied whether …
Source: ascopubs.orgCategories: General Medicine News, Hem/OncsTweet-
Another study where #radiotherapy dose escalation (PET guided 71 Gy vs 60 Gy) did not improve outcomes🤔 Disappointing Sample size feels small to find dose response IMO 2-yr local control of 55-60% clearly highlights need for treatment intensification⚠️ https://t.co/oEdglmcVsq
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Mashup Score: 75Radiotherapy Improves Survival in NSCLC After Oligoprogression on Immunotherapy: A Cohort Study - 9 month(s) ago
The patterns of oligoprogression after first-line immune checkpoint inhibitors (ICIs) for metastatic NSCLC are yet to be well established. An increasing volume of data suggests that directed radiotherapy improves survival outcomes in patients with progression after ICIs.
Source: www.jtocrr.orgCategories: General Medicine News, Oncologists1Tweet-
Very intresting paper by Brown, @RadOncDoc_Gee @Eric73363938 et al, from 🇦🇺 They report outcomes in patients with oligoprogression following 1st line IO or ChemoIO 🚨Patients who receive #radiotherapy have better survival Paper link on @JTOonline : 🔗https://t.co/zISggmxpdA https://t.co/2eXnQrKgKY
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Mashup Score: 36Stereotactic vs Hypofractionated Radiotherapy for Inoperable Stage I Non–Small Cell Lung Cancer - 9 month(s) ago
This randomized clinical trial examines whether stereotactic body radiotherapy improves local control compared with hypofractionated conventional radiotherapy.
Source: jamanetwork.comCategories: General Medicine News, Hem/OncsTweet-
📢Important trial SBRT 48/4, 60/8 v Hypofx 60/15 #radiotherapy in stage I NSCLC Well done👏 Several interpretations here What does "Severe toxic effects were limited" mean for patients? IMHO it supports 60Gy/3w for central NSCLC @DrAlexLouie @Dr_RayMak https://t.co/1JeMo08TtW
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Mashup Score: 10New method could lower radiotherapy doses for some cancer patients - 11 month(s) ago
A special type of MRI scan where patients inhale 100% oxygen could result in lower radiotherapy doses for some cancer patients.
Source: www.icr.ac.ukCategories: General Medicine News, Oncologists1Tweet-
📰NEWS: Researchers at the ICR and @OfficialUoM have developed a new method that could lower the #radiotherapy doses for some cancer patients. Read more about their oxygen-enhanced magnetic resonance imaging ⤵️ https://t.co/I0DkUxu8zB
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Children experience multiple adverse symptoms when undergoing #radiotherapy, with 3 distinct symptom profiles dominating. Published in @Cancer_Nursing. https://t.co/4QrAcEH23c