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Mashup Score: 13Toward the End of Planning Target Volume Margins With Online Adaptive Radiation Therapy - 23 day(s) ago
Radiation therapy aims to cure patients by delivering the prescribed dose to the tumor with high precision. In the presence of positioning uncertainties, the question arises how to ensure that the actual given dose to a patient’s tumor is sufficient. To address this challenge, the planning target volume (PTV) was introduced in International Commission on Radiation Units and Measurements (ICRU) Report 501 as a geometric margin around the target. Various groups proposed margin “recipes” to determine their adequate size.
Source: www.redjournal.orgCategories: General Medicine NewsTweet
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Mashup Score: 13Toward the End of Planning Target Volume Margins With Online Adaptive Radiation Therapy - 23 day(s) ago
Radiation therapy aims to cure patients by delivering the prescribed dose to the tumor with high precision. In the presence of positioning uncertainties, the question arises how to ensure that the actual given dose to a patient’s tumor is sufficient. To address this challenge, the planning target volume (PTV) was introduced in International Commission on Radiation Units and Measurements (ICRU) Report 501 as a geometric margin around the target. Various groups proposed margin “recipes” to determine their adequate size.
Source: www.redjournal.orgCategories: General Medicine NewsTweet
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Mashup Score: 50
Nature – Immune checkpoint blockade activates T cell immunity by reprogramming the STAT3 and STAT5 transcriptional pathways in dendritic cells, and STAT3 degradation is effective for treating…
Source: www.nature.comCategories: General Medicine NewsTweet
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Mashup Score: 28Radiation-induced amphiregulin drives tumour metastasis - 2 month(s) ago
Nature – Radiotherapy induces expression of the EGFR ligand amphiregulin, which promotes metastasis growth at remote sites in mouse models and human patients by shifting myeloid cells towards an…
Source: www.nature.comCategories: General Medicine NewsTweet
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Mashup Score: 28Radiation-induced amphiregulin drives tumour metastasis - 2 month(s) ago
Nature – Radiotherapy induces expression of the EGFR ligand amphiregulin, which promotes metastasis growth at remote sites in mouse models and human patients by shifting myeloid cells towards an…
Source: www.nature.comCategories: General Medicine NewsTweet
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Mashup Score: 47
PURPOSETo test whether dose-escalated single fraction (SF) stereotactic body radiotherapy (SBRT) of 20 Gy to painful bone metastases is superior to conventional SF three-dimensional (3D) conformal radiotherapy (RT) to a standard dose of 8 Gy in achieving …
Source: ascopubs.orgCategories: General Medicine NewsTweet
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Mashup Score: 40
PURPOSETo test whether dose-escalated single fraction (SF) stereotactic body radiotherapy (SBRT) of 20 Gy to painful bone metastases is superior to conventional SF three-dimensional (3D) conformal radiotherapy (RT) to a standard dose of 8 Gy in achieving …
Source: ascopubs.orgCategories: General Medicine NewsTweet
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Mashup Score: 10Sharper Focus, Greater Comfort? Lessons From the ROBOMET Trial - 2 month(s) ago
Radiotherapy is an established standard of care for palliation of painful bone metastases, yet the debate over the optimal dose and fractionation remains unresolved. Radiation oncologists have long found themselves grappling with the same question—should treatment be delivered in 10 fractions, 5 fractions, or perhaps just a single convenient session? In the article that accompanies this editorial, Mercier et al 18 have published the results of a phase III randomized control trial of conventional external
Source: ascopubs.orgCategories: General Medicine NewsTweet
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Mashup Score: 38
PURPOSETo test whether dose-escalated single fraction (SF) stereotactic body radiotherapy (SBRT) of 20 Gy to painful bone metastases is superior to conventional SF three-dimensional (3D) conformal radiotherapy (RT) to a standard dose of 8 Gy in achieving …
Source: ascopubs.orgCategories: General Medicine NewsTweet
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Mashup Score: 3
: Optimal treatment strategies for patients with hepatocellular carcinoma (HCC) with oligoprogression after first-line systemic therapy (FLST) remain undefined. We aimed to determine if maintaining [i.e., continuing] FLST plus radiotherapy for oligoprogressive lesions (m-FLST + RT) would result in progression-free survival (PFS) equal to or greater than that of second-line systemic therapy (s-SLST), either alone or with radiotherapy (s-SLST + RT).
Source: www.redjournal.orgCategories: General Medicine News, Hem/OncsTweet
RT @DavidSherMD: Eliminating the PTV as a concept is a provocative idea. This editorial is worth a read... https://t.co/c9Q0BEPq0C