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Mashup Score: 17
The development of the cerebral cortex largely depends on the stem cells responsible for generating neurons, known as radial glial cells. Until now, it was believed that these stem cells generated neurons …
Source: medicalxpress.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 20An iron rheostat controls hematopoietic stem cell fate - 2 month(s) ago
The preservation of adult stem cell identity following cell division is essential for sustained tissue maintenance and repair. Will, Kao, and colleagues identify iron as a crucial regulator allowing hematopoietic stem cells to orchestrate metabolic and gene regulatory control during regenerative fate determination.
Source: www.cell.comCategories: General Medicine News, Hem/OncsTweet-
RT @CellStemCell: Online Now! An iron rheostat controls hematopoietic stem cell fate https://t.co/dcL5Apew16 #stemcells
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Mashup Score: 0
An abstract is unavailable.
Source: journals.lww.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
The #FDA has approved #motixafortide in combination with #filgrastim to mobilize hematopoietic #stemcells to the peripheral blood for collection and subsequent autologous transplantation in patients with #multiplemyeloma. https://t.co/YmaNYOaXGc https://t.co/HAoMUmnyHc
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Mashup Score: 0
An abstract is unavailable.
Source: journals.lww.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
#GVHD, in which donated cells attack the patient's own healthy cells, is a common side effect for patients receiving #stemcells from a donor. Researchers have identified #riskbiomarkers to ensure GVHD is caught early. https://t.co/h3nO1Q4BTS #CancerResearch https://t.co/D99LirJmiA
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Mashup Score: 0
An abstract is unavailable.
Source: journals.lww.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
For #bloodcancer patients, receiving #stemcells offers the possibility of a cure. But, patients undergoing allogeneic hematopoietic cell transplantation also face the possibility of a common side effect—graft-versus-host disease (GVHD). https://t.co/1z3Uipb92r #GVHD https://t.co/byygPW23av
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Mashup Score: 7Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction - 7 month(s) ago
Whole-exome sequencing of autism spectrum disorder (ASD) probands and unaffected family members has identified many genes harboring de novo variants s…
Source: www.sciencedirect.comCategories: General Medicine News, Latest HeadlinesTweet-
Precise gene editing in human #stemCells and neurons reveals links between genome organization and #autism @nygenome @AJHGNews https://t.co/PwXU6l9LZC https://t.co/is8on4POi2
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Mashup Score: 4GDF11 inhibits abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis | Bone & Joint - 8 month(s) ago
GDF11 inhibits abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis
Source: boneandjoint.org.ukCategories: Latest Headlines, RheumatologyTweet-
This is the first time that the inhibitory role of GDF11 in lipid formation of chondrocytes through the induction of PPARγ SUMOylation has been disclosed. These findings could provide a new view on the understanding of OA. #Osteoarthritis #StemCells #BJR https://t.co/7iqmzTdnRX https://t.co/Hp4nKW3fys
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Mashup Score: 6Dual CRISPR-Cas3 system for inducing multi-exon skipping in DMD patient-derived iPSCs - 8 month(s) ago
Kita et al. utilize the dual CRISPR-Cas3 system to induce a large deletion (∼340 kb) at the dystrophin exon 45–55 region for multi-exon skipping (MES) in various Duchenne muscular dystrophy (DMD) mutation patterns. Dual-Cas3-based MES restored dystrophin protein in DMD-iPSCs without significant off-target deletion. Dual CRISPR-Cas3 is a promising tool for MES induction to restore dystrophin protein in DMD.
Source: www.cell.comCategories: General Medicine News, Latest HeadlinesTweet-
Dual #CRISPR-Cas3 restores dystrophin function in #stemcells derived from patients with Duchenne muscular dystrophy. Read more in @stemcellreports https://t.co/NkL5DsSduL @CiRA_KU_J Akitsu Hotta https://t.co/IKPi0S3KrF
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Mashup Score: 8Dual CRISPR-Cas3 system for inducing multi-exon skipping in DMD patient-derived iPSCs - 8 month(s) ago
Kita et al. utilize the dual CRISPR-Cas3 system to induce a large deletion (∼340 kb) at the dystrophin exon 45–55 region for multi-exon skipping (MES) in various Duchenne muscular dystrophy (DMD) mutation patterns. Dual-Cas3-based MES restored dystrophin protein in DMD-iPSCs without significant off-target deletion. Dual CRISPR-Cas3 is a promising tool for MES induction to restore dystrophin protein in DMD.
Source: www.cell.comCategories: General Medicine News, Latest HeadlinesTweet-
Dual #CRISPR-Cas3 restores dystrophin function in #stemcells derived from patients with Duchenne muscular dystrophy. Read more in @stemcellreports https://t.co/NkL5DsSduL @CiRA_KU_J Akitsu Hotta https://t.co/fmQeCP7jiZ
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Mashup Score: 7A 'memory wipe' for stem cells may be the key to better therapies - 8 month(s) ago
Stem cells are special kinds of cells in our body that can become any other type of cell. They have huge potential for medicine, and trials are currently under way using stem cells to replace damaged …
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet-
A 'memory wipe' for #stemcells may be the key to better therapies @ConversationEDU @nature https://t.co/13ou0bD45q
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Study uncovers multiple lineages of #stemCells contributing to neuron production @UniversidadMH @ScienceAdvances https://t.co/hAhcEe8Eq9