For microbiome research to be translated into clinical applications, the field needs to move beyond correlational studies; we suggest adopting a multi-phase iterative approach that leverages in vivo and ex vivo strategies, as well as a combination of traditional microbiology, with big-data approaches.

Recordings from electrocorticography brain-computer interface (BCI) in tetraplegic participants find mesoscale representational stability and plasticity with neurofeedback that allows for long-term neuroprosthetic control of a robotic arm and hand.

Genomic analysis of the amphipod Hirondellea gigas revealed population homogeneity within the Mariana Trench but genetic differentiation between nearby hadal features. Multi-omics analysis showed that host-symbiotic interactions contribute to its adaptation to high-pressure and food-limited hadal environments.