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Mashup Score: 0Celldex drug reduces chronic hive activity, but patient discontinuations raise questions - 17 hour(s) ago
Celldex Therapeutics reported that its medicine for a condition that causes chronic hives reduced hive activity and, notably, did not raise any safety concerns.
Source: www.statnews.comCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 15T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vessels - 21 hour(s) ago
How T cells are recruited to brain tumors from the blood remains unclear. Messmer et al. identify peritumoral venous vessels (PVVs) as key structures for T cell recruitment to melanoma brain tumors. PVVs are the sites of T cell extravasation and facilitated rapid T cell migration under immune checkpoint inhibition. T cell recruitment and antitumor immunity were dependent on ICAM-1.
Source: www.cell.comCategories: General Medicine News, Allergy-ImmunologyTweet-
RT @LukensJohnR: T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vessels: @ImmunityCP https://t.co/Gz4XoF46ee…
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Mashup Score: 59Maintenance of X chromosome inactivation after T cell activation requires NF-κB signaling - 1 day(s) ago
X chromosome inactivation maintenance, including Xist RNA localization to the inactive X, requires canonical NF-κB signaling in T cells.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research suggests that #NFκB signaling is necessary to maintain #Xchromosome inactivation after T cell activation. Read more in Science #Immunology: https://t.co/eZ82Mhz6Sg @montserrat @pennvet https://t.co/VFPNTXJ4Cd
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Mashup Score: 7
Orismilast outperformed placebo in the treatment of moderate to severe atopic dermatitis in adults, according to a poster presented at the European Academy of Dermatology and Venereology Congress. “Orismilast is a potent, selective phosphodiesterase 4 (PDE4)-B and -D inhibitor, which showed significant efficacy in a phase 2b psoriasis study,” Eric L. Simpson, MD, MCR, Frances J.
Source: www.healio.comCategories: General Medicine News, Allergy-ImmunologyTweet-
#Orismilast outperformed placebo in the treatment of moderate to severe #atopic #dermatitis in adults, according to a poster presented at the European Academy of #Dermatology and Venereology Congress. https://t.co/ZvlUPf7qbo https://t.co/KBk5SlUH35
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Mashup Score: 1Murine parainfluenza virus persists in lung innate immune cells sustaining chronic lung pathology - 1 day(s) ago
Nature Microbiology – Murine parainfluenza virus (Sendai) persists and imprints lung innate immune cells, leaving long-lasting transcriptomic alterations associated with type-2 inflammation and…
Source: www.nature.comCategories: General Medicine News, Allergy-ImmunologyTweet-
Interesting. Could chronic viral persistence drive chronic inflammatory diseases like asthma and COPD? https://t.co/wK9wlsEPll
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Mashup Score: 5Nobel Laureates - The American Association of Immunologists - 2 day(s) ago
Nobel Prize winning members of The American Association of Immunologists
Source: www.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
#DYK that AAI boasts 27 Nobel Laureates among its past and current members? Before the @NobelPrize announcements begin, we're highlighting some of our Nobel Laureates and their achievements: https://t.co/EYfIQiqmia. #Immunology #NobelPrize https://t.co/96YngMJ5Cn
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Mashup Score: 0Donny & Marie Show - Star Wars Special (1977) - 2 day(s) ago
The finale of this show was a tribute to Star Wars. Donny Osmond played Luke, his sister Marie played Luke’s sister Leia (spoilers!) and Kris Kristofferson w…
Source: www.youtube.comCategories: General Medicine News, Allergy-ImmunologyTweet-
We were once a proper country https://t.co/9qaJrnDdzo
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Mashup Score: 6Avoid the Danger of Anaphylaxis this Halloween | AAAAI - 2 day(s) ago
The AAAAI offers tips written and reviewed by experts on allergies on avoiding the danger of anaphylaxis this Halloween.
Source: www.aaaai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Ghosts & goblins aren’t the only scary things you might see this Halloween. For parents of kids with #FoodAllergies, Halloween treats can be frightening. Be cautious of “fun size” candy, which may have different ingredients than regular size packages. https://t.co/h9wjWGQEFw https://t.co/H529wYCvU3
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Mashup Score: 151Contents | Science Immunology 9, 100 - 2 day(s) ago
ONLINE COVER Sex-Biased Gene Regulation in T Cells. In females, X chromosome inactivation (XCI) represses gene expression from one X chromosome to balance gene dosage between the sexes. This process is controlled by the long noncoding RNA Xist, which coats the inactive X chromosome and promotes epigenetic gene silencing. Forsyth et al. studied XCI in mouse and human T cells, a process that is much more dynamic in T cells than in most other somatic cells. NF-κB signaling downstream of the T cell receptor
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Science #Immunology's October issue is out! This month's cover highlights how #NFkB signaling helps recruit the noncoding RNA Xist to maintain #XChromosomeInactivation in activated T cells. Read this research and more: https://t.co/sfmAjsRlhs https://t.co/x7cQ9xfZOj
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Mashup Score: 80
How T cells are recruited to brain tumors from the blood remains unclear. Messmer et al. identify peritumoral venous vessels (PVVs) as key structures for T cell recruitment to melanoma brain tumors. PVVs are the sites of T cell extravasation and facilitated rapid T cell migration under immune checkpoint inhibition. T cell recruitment and antitumor immunity were dependent on ICAM-1.
Source: www.cell.comCategories: General Medicine News, Allergy-ImmunologyTweet-
Online now: T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vessels https://t.co/BmqMcQWQGH
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https://t.co/0iazR6CZao new chronic urticaria therapy: 25% of patients who started the study on barzolvolimab stopped treatment during the trial, changes in hair and skin color reported