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Mashup Score: 0Treating DCIS: To Escalate or De-escalate? - 15 hour(s) ago
There is much debate about the necessity of treating women with ductal carcinoma in situ (DCIS) with surgery or radiotherapy. 1,2 It is disconcerting to many that patients with DCIS are treated in the same way as are women with early-stage invasive breast cancer. Many patients with DCIS have bilateral mastectomies. 2 Much effort is being expended to identify women at sufficiently low risk who might avoid surgery and/or radiotherapy. 3-9 In a recent paper from the UK, Mannu et al followed women with DCIS
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Mashup Score: 1AI Model May Help Predict Treatment Responses, Select Most Effective Cancer Therapies in Patients With Cancer - 18 hour(s) ago
Can a novel artificial intelligence (AI) model accurately predict how patients with cancer will respond to certain cancer drugs? A recent study investigated.
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Mashup Score: 8Sophia McKinley, MD, EdM, on Cutaneous Melanoma: Outcomes With Adjuvant Immunotherapy - 2 day(s) ago
Sophia McKinley, MD, EdM, of Massachusetts General Hospital, discusses patterns of recurrence in patients with resected cutaneous melanoma during or after adjuvant immunotherapy. She identifies the risk factors associated with overall survival and treatment failure (Abstract 60). Jenny H. Chang, MD, of the Cleveland Clinic, discusses the current surgical and radiologic treatment paradigm for patients with stage III Merkel cell carcinoma and the potential for neoadjuvant immunotherapy to help manage the
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Mashup Score: 1
In a prospective cohort study, among patients hospitalized due to COVID-19 infection, those receiving cancer treatment had a higher rate of in-hospital mortality vs those without a cancer diagnosis.
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Mashup Score: 5Imaging Drug to Assist in Detection of Cancerous Tissue Following Lumpectomy Approved - 2 day(s) ago
Recently, the FDA approved pegulicianine (Lumisight) for adult patients with breast cancer to assist in the intraoperative detection of cancerous tissue within the resection cavity following removal o…
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Mashup Score: 8Sophia McKinley, MD, EdM, on Cutaneous Melanoma: Outcomes With Adjuvant Immunotherapy - 2 day(s) ago
Sophia McKinley, MD, EdM, of Massachusetts General Hospital, discusses patterns of recurrence in patients with resected cutaneous melanoma during or after adjuvant immunotherapy. She identifies the risk factors associated with overall survival and treatment failure (Abstract 60). Jenny H. Chang, MD, of the Cleveland Clinic, discusses the current surgical and radiologic treatment paradigm for patients with stage III Merkel cell carcinoma and the potential for neoadjuvant immunotherapy to help manage the
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Mashup Score: 3
The FDA approved lutetium Lu-177 dotatate (Lutathera) for pediatric patients aged 12 years and older with somatostatin receptor–positive gastroenteropancreatic neuroendocrine tumors (GEP-NETs)—includi…
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Mashup Score: 4FDA Grants Accelerated Approval to Tovorafenib for Patients With Relapsed or Refractory BRAF-Altered Pediatric Low-Grade Glioma - 3 day(s) ago
On April 23, the FDA granted accelerated approval to the type II RAF inhibitor tovorafenib (Ojemda) for patients 6 months of age and older with relapsed or refractory pediatric low-grade glioma harbor…
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Mashup Score: 1Wendy Vogel, MSN, FNP, AOCNP, FAPO, on the Evolving Role of Advanced Practice Providers in Oncology Care - 3 day(s) ago
Wendy Vogel, MSN, FNP, AOCNP, FAPO, of the Advanced Practitioner Society for Hematology and Oncology, summarizes a panel discussion in which she took part, on forming interprofessional oncology care teams that include advanced practitioners. Such collaboration may improve patient outcomes and help practices work more efficiently. Natalie S. Callander, MD, of the University of Wisconsin Carbone Cancer Center, discusses advances in the treatment of patients with multiple myeloma, including her commentary
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Mashup Score: 4Induction and Concurrent Vismodegib With Radiation Therapy for Locally Advanced Unresectable Basal Cell Carcinoma - 3 day(s) ago
In a phase II study reported in the Journal of Clinical Oncology, Barker et al found that induction treatment with vismodegib followed by concurrent treatment with vismodegib and curative-intent radia…
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Steven A. Narod, MD, on Treating DCIS: To Escalate or De-escalate? https://t.co/kFROr8dQ9h #bcsm #breastcancer #DCIS #oncology @WCHospital @UofT_dlsph @WCHResearch