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Mashup Score: 1Addition of Durvalumab to Gemcitabine/Cisplatin in Advanced Biliary Tract Cancer: PROs in TOPAZ-1 - 2 hour(s) ago
A patient-reported outcome (PRO) analysis from the phase III TOPAZ-1 trial showed no “detrimental effect” with the addition of durvalumab to gemcitabine/cisplatin in patients with advanced biliary tra…
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Mashup Score: 3
Adding the phosphatidylserine-targeting antibody bavituximab to the immunotherapy agent pembrolizumab may improve response rates without compromising safety in patients with hepatocellular carcinoma, …
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Mashup Score: 2Effect of Radiation Therapy Timing on Lifespan of Artificial Urinary Sphincters in Prostate Cancer Survivors - 21 hour(s) ago
Researchers have investigated whether adjuvant radiation therapy may improve the function of artificial urinary sphincters for stress urinary incontinence in patients who have undergone surgery for pr…
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Mashup Score: 3
Adding the phosphatidylserine-targeting antibody bavituximab to the immunotherapy agent pembrolizumab may improve response rates without compromising safety in patients with hepatocellular carcinoma, …
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Mashup Score: 2T-DXd vs Physician’s Choice of Therapy in HER2-Positive Metastatic Breast Cancer: PROs in DESTINY-Breast02 - 23 hour(s) ago
An analysis of patient-reported outcomes (PROs) in the DESTINY-Breast02 trial found that general health status/quality of life was maintained over time with fam-trastuzumab deruxtecan-nxki (T-DXd) vs …
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Mashup Score: 3For Detection of Measurable Residual Disease in Ovarian Cancer, Are Two Methods Better Than One? - 1 day(s) ago
In patients with ovarian cancer, second-look surgery may find a role again. The evaluation of measurable residual disease (MRD) using second-look laparoscopy identified more women who had detectable M…
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Mashup Score: 5Hemihepatectomy: Outcomes With Laparoscopic vs Open Surgery - 1 day(s) ago
In a phase III study, investigators found that among patients with indications for hemihepatectomy suitable for both laparoscopic and open approaches, of whom the majority had cancer, the laparoscopic…
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Mashup Score: 1Breast-Conserving Therapy in BRCA-Mutation Carriers: Study Looks at Long-Term Outcomes - 2 day(s) ago
Recent research has provided valuable insights into the long-term outcomes of patients with pathogenic BRCA1 and BRCA2 mutations who undergo breast-conserving therapy, according to a study presented a…
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Mashup Score: 1Durvalumab After Chemoradiotherapy in Unresectable NSCLC: Real-World Use and Outcomes - 2 day(s) ago
In a retrospective cohort study (SPOTLIGHT), investigators found that a substantial proportion of patients with unresectable stage III NSCLC did not receive consolidation durvalumab after chemoradioth…
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Mashup Score: 5Dato-DXd in Advanced or Metastatic HR-Positive/HER2-Negative or Triple-Negative Breast Cancer - 2 day(s) ago
Results from the phase I TROPION-PanTumor01 trial showed that the antibody-drug conjugate datopotamab deruxtecan was active in patients with locally advanced or metastatic hormone receptor (HR)-positi…
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Addition of Durvalumab to Gemcitabine/Cisplatin in Advanced Biliary Tract Cancer: PROs in TOPAZ-1 https://t.co/34rD3F54kk #hpbcsm #bileductcancer #cholangiocarcinoma #oncology #immunotherapy