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Mashup Score: 20
View all available purchase options and get full access to this article. Jeger RV, Eccleshall S, Wan Ahmad WA, Ge J, Poerner TC, Shin ES, Alfonso F, Latib A, Ong PJ, Rissanen TT, et al; International DCB Consensus Group. Drug-coated balloons for coronary artery disease: third report of the International DCB Consensus Group. JACC Cardiovasc Interv. 2020;13:1391–1402. doi: 10.1016/j.jcin.2020.02.043 Leone PP, Heang TM, Yan LC, Perez IS, Caiazzo G, Geraci S, Jiyen K, Tomai F, Buccheri D, Seresini G, et al.
Source: www.ahajournals.orgCategories: General Medicine NewsTweet
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Mashup Score: 40
BACKGROUND: Acute decompensated aortic stenosis is an increasingly common condition associated with a high rate of morbidity, mortality, and health care resource utilization. Among patients with acute decompensated aortic stenosis, this study aimed to assess the impact of time to transcatheter aortic valve implantation (TAVI) on outcomes, hypothesizing that longer durations are associated with worse outcomes. METHODS: Using a single-center registry, patients with their first presentation of acute decompensated aortic stenosis who underwent an urgent TAVI during their index admission were included. Time to TAVI was defined as the number of days between hospital admission and TAVI. The primary composite outcome was heart failure hospitalization or all-cause mortality. The secondary composite outcome was heart failure hospitalization or cardiovascular mortality. RESULTS: A total of 276 patients were included in this study: age 84 (79–88) years, male sex 63.7%, patients requiring cardiopul
Source: www.ahajournals.orgCategories: General Medicine NewsTweet-
How fast can you get your Aortic Stenosis patient thru the system.? Time matters in TAVI candidates with decompensated aortic stenosis #AHAJournals @MichaelMc_Kenna @ThomasTreibel @guyll @Echo_Imaging @bartstructural https://t.co/a16gOM6i89 https://t.co/BYVuWKYpJN
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Mashup Score: 27
BACKGROUND: Access-related vascular and bleeding complications during transcatheter aortic valve implantation (TAVI) are associated with significant morbidity and mortality. Ultrasound-guided (USG) puncture may reduce the incidence of these adverse events, particularly in large-bore arterial access. However, large-scale data on this approach are limited, and it has not yet been fully implemented into standard clinical practice. We compared access-related vascular and bleeding complications in USG versus fluoroscopy-guided access from a large multicenter TAVI registry. METHODS: The Plug- or Suture-Based Vascular Closure After TAVI registry retrospectively evaluated data of 9295 patients who underwent transfemoral TAVI at 10 high-volume German heart centers (2016–2021). USG and fluoroscopy-guided access were performed in 1992 (21.4%) and 7303 (78.6%) patients, respectively. Propensity score matching (1:1) yielded 895 matched pairs. The primary end point, a composite of minor and major va
Source: www.ahajournals.orgCategories: General Medicine NewsTweet-
How do you gain femoral access in TAVI? Ultrasound can lower rate of access related complications. A report from a multicenter TAVI-Registry @wonkeunkim1 @MattiAdam_MD @Card_Vasc_MMM @HWienemann @HenrykDreger @david.grundmann1 #AHAJournals https://t.co/ocpyWW1NTu https://t.co/4T7lnI7iWc
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Mashup Score: 27
BACKGROUND: Access-related vascular and bleeding complications during transcatheter aortic valve implantation (TAVI) are associated with significant morbidity and mortality. Ultrasound-guided (USG) puncture may reduce the incidence of these adverse events, particularly in large-bore arterial access. However, large-scale data on this approach are limited, and it has not yet been fully implemented into standard clinical practice. We compared access-related vascular and bleeding complications in USG versus fluoroscopy-guided access from a large multicenter TAVI registry. METHODS: The Plug- or Suture-Based Vascular Closure After TAVI registry retrospectively evaluated data of 9295 patients who underwent transfemoral TAVI at 10 high-volume German heart centers (2016–2021). USG and fluoroscopy-guided access were performed in 1992 (21.4%) and 7303 (78.6%) patients, respectively. Propensity score matching (1:1) yielded 895 matched pairs. The primary end point, a composite of minor and major va
Source: www.ahajournals.orgCategories: General Medicine NewsTweet-
How do you gain femoral access in TAVI? Ultrasound can lower rate of access related complications. A report from a multicenter TAVI-Registry @wonkeunkim1 @MattiAdam_MD @Card_Vasc_MMM @HWienemann @HenrykDreger @david.grundmann1 #AHAJournals https://t.co/ocpyWW1NTu https://t.co/4T7lnI7iWc
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Mashup Score: 35Randomized Study Comparing Angiography Guidance With Physiology Guidance After PCI: The EASY-PREDICT Study | Circulation: Cardiovascular Interventions - 1 month(s) ago
BACKGROUND: Physiology assessment of coronary lesion prepercutaneous coronary intervention (PCI) using hyperemic and nonhyperemic pressure ratios is useful to determine if a lesion requires treatment. Whether the physiology after PCI is superior to angiography guidance only is unknown. The study sought to investigate whether post-PCI physiology improves clinical outcomes compared with standard angiographic guidance. METHODS: All-comers patients referred for diagnostic angiography and possible PCI were recruited in a high-volume tertiary care hospital. After uncomplicated PCI, patients were randomized to angiography guidance or target vessel physiology, including nonhyperemic pressure ratio (resting distal coronary pressure to aortic pressure ratio and diastolic pressure ratio) and fractional flow reserve. The primary outcome was the rate of target vessel failure, including cardiac death, myocardial infarction, and target vessel revascularization at 18 months post-PCI. Angina score, med
Source: www.ahajournals.orgCategories: General Medicine NewsTweet-
How good are your eyes? What is the impact of post-PCI physiology guidance versus angiography guidance on clinical outcomes in routine PCI? The EASY-PREDICT Study presented @PCRonline #EuroPCR & published simultaneously @EuroInterventio #AHAJournals https://t.co/BMJ3dluZLY https://t.co/VCjRISrxrT
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Mashup Score: 35Randomized Study Comparing Angiography Guidance With Physiology Guidance After PCI: The EASY-PREDICT Study | Circulation: Cardiovascular Interventions - 1 month(s) ago
BACKGROUND: Physiology assessment of coronary lesion prepercutaneous coronary intervention (PCI) using hyperemic and nonhyperemic pressure ratios is useful to determine if a lesion requires treatment. Whether the physiology after PCI is superior to angiography guidance only is unknown. The study sought to investigate whether post-PCI physiology improves clinical outcomes compared with standard angiographic guidance. METHODS: All-comers patients referred for diagnostic angiography and possible PCI were recruited in a high-volume tertiary care hospital. After uncomplicated PCI, patients were randomized to angiography guidance or target vessel physiology, including nonhyperemic pressure ratio (resting distal coronary pressure to aortic pressure ratio and diastolic pressure ratio) and fractional flow reserve. The primary outcome was the rate of target vessel failure, including cardiac death, myocardial infarction, and target vessel revascularization at 18 months post-PCI. Angina score, med
Source: www.ahajournals.orgCategories: General Medicine NewsTweet-
How good are your eyes? What is the impact of post-PCI physiology guidance versus angiography guidance on clinical outcomes in routine PCI? The EASY-PREDICT Study presented @PCRonline #EuroPCR & published simultaneously @EuroInterventio #AHAJournals https://t.co/BMJ3dluZLY https://t.co/VCjRISrxrT
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Mashup Score: 69
BACKGROUND: Valve-in-valve transcatheter aortic valve replacement (ViV-TAVR) provides an alternative treatment for high-risk patients with failed surgical bioprosthetic aortic valves. However, limited data exist on ViV-TAVR outcomes in patients with small aortic annuli, particularly among the relatively small-statured Japanese population. METHODS: We analyzed data from the J-TVT (Japan Transcatheter Valve Therapy) registry, which included all TAVR institutions across Japan, with data collected from July 2018, when ViV-TAVR was approved, through December 2022. A small aortic annulus was defined as an aortic annulus area of ≤314 mm², measured using preoperative computed tomography for ViV-TAVR. Prosthesis-patient mismatch (PPM) was defined as an indexed effective orifice area <0.85 cm²/m², assessed using echocardiography within 30 days after ViV-TAVR. The composite endpoint was evaluated at 30 days and 1 year. RESULTS: Among 47 800 individuals, 1029 underwent ViV-TAVR, resulting in a fin
Source: www.ahajournals.orgCategories: General Medicine NewsTweet-
Valve-in-valve TAVR is safe and effective for small aortic annuli. A report from a Japanese Nationwide Registry presented @PCRonline #EuroPCR and published simultaneously @OhnoTuri @EuroInterventio #AHAJournals #cardiotwitter https://t.co/4y1neSvYey https://t.co/TgmNTdvhcr
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Mashup Score: 33Long-Term Safety and Efficacy of Renal Denervation: 24-Month Results From the SPYRAL HTN-ON MED Trial | Circulation: Cardiovascular Interventions - 1 month(s) ago
BACKGROUND: Six-month results from the SPYRAL HTN-ON MED trial demonstrated that renal denervation (RDN) reduced office blood pressure (BP), and not 24-hour ambulatory systolic BP, compared with sham control in hypertensive patients. In this prespecified analysis of the ON MED trial, long-term changes in BP, antihypertensive drug use, and safety outcomes through 24 months are compared between RDN and sham control groups. METHODS: SPYRAL HTN-ON MED is a prospective, randomized, sham-controlled, blinded trial enrolling 337 patients globally from 56 clinical centers. Eligible patients had an office systolic BP of 150 to 180 mm Hg, a diastolic BP ≥90 mm Hg, and a 24-hour ambulatory systolic BP of 140 to 170 mm Hg. Patients were randomized to RDN or a sham control procedure and were prescribed a stable regimen of 1 to 3 antihypertensive medications through 6 months. After 6 months, patients and physicians were unblinded with permitted changes to antihypertensive therapy, and control patient
Source: www.ahajournals.orgCategories: General Medicine NewsTweet-
Sustained BP reduction at 2-years following renal denervation. 24-month results from the SPYRAL HTN-ON MED Trial @FelixMahfoud @Kandzari #cardiotwitter #AHAJournals https://t.co/xWNYjHg7Nw https://t.co/GOHKjz9VE0
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Mashup Score: 5510-Year Outcomes of Deferred or Conventional Stent Implantation in Patients With STEMI (DANAMI-3-DEFER) | Circulation: Cardiovascular Interventions - 1 month(s) ago
BACKGROUND: Primary percutaneous coronary intervention (PCI) with stenting is recommended in ST-segment–elevation myocardial infarction. Immediate stenting may cause distal embolization, microvascular damage, and flow disturbances, leading to adverse outcomes. We report the 10-year clinical outcomes of deferred stenting versus conventional PCI in patients with ST-segment–elevation myocardial infarction. METHODS: We conducted a 10-year follow-up study of the open-label, randomized DANAMI-3-DEFER trial (Third Danish Study of Optimal Acute Treatment of Patients With STEMI – Deferred Stent Implantation Versus Conventional Treatment), conducted in 4 PCI centers in Denmark. Patients with ST-segment–elevation myocardial infarction and acute chest pain 24 hours after the index procedure or conventional PCI with immediate stenting. In the deferred group, immediate stable Thrombolysis in Myocardial Infarction flow II to III was established, and int
Source: www.ahajournals.orgCategories: General Medicine News, Cardiology News and JournTweet-
Is deferring immediate stenting in #STEMI of benefit? 10-Year Outcomes of Deferred or Conventional Stent Implantation in Patients with STEMI. The DANAMI-3-DEFER Study presented @PCRonline #EuroPCR and published simultaneously @EuroInterventio #AHAJournals https://t.co/DuHUMM8SJT https://t.co/T1SLhqaqrA
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Mashup Score: 66
View all available purchase options and get full access to this article. Sakai K, Mizukami T, Leipsic J, Belmonte M, Sonck J, Nørgaard BL, Otake H, Ko B, Koo BK, Maeng M, et al. Coronary atherosclerosis phenotypes in focal and diffuse disease. JACC Cardiovasc Imaging. 2023;16:1452–1464. doi: 10.1016/j.jcmg.2023.05.018 Biscaglia S, Guiducci V, Escaned J, Moreno R, Lanzilotti V, Santarelli A, Cerrato E, Sacchetta G, Jurado-Roman A, Menozzi A, et al; FIRE Trial Investigators. Complete or culprit-only PCI in
Source: www.ahajournals.orgCategories: General Medicine NewsTweet-
Coronary Atherosclerosis Phenotypes in Non-Flow-Limiting Nonculprit Lesions. Focal CAD lesions may be worse than diffuse disease patterns. Presented @PCRonline #EuroPCR and published simultaneously @EuroInterventio #AHAJournals #cardiotwitter @matser89 https://t.co/SW25WZHojR https://t.co/Y6j9ppjuEV
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Do female patients respond differently than males? Higher 2-year MACE after sirolimus-coated balloon angioplasty for female patients with in-stent restenosis. A hypothesis generating research letter @Dr.LucaTesta @leoneppmd @AGrecoMD @Dari08s https://t.co/oSMRqCSJo1 https://t.co/fNL7bgy5o3