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Mashup Score: 0Cognitive behavioural therapy for the treatment of schizophrenia spectrum disorders: an umbrella review of meta-analyses of randomised controlled trials - 13 hour(s) ago
Findings suggest that the effectiveness of CBT on general and positive symptoms in SSD at EoT was small to medium, while we found inconsistent evidence for a sustainable effect. CBT has no convincing impact on other relevant outcomes. Guidelines may use these results to specify their recommendations.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0
Up to one year after it ended, a health system intervention resulted in sustained increases in the number of HHC identified and starting TPT. A simplified version of the intervention was associated with non-significant increases in the identification and treatment of HHC. Inferences are limited by potential bias due to other temporal effects, and the small number of study sites.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 3Andrew Yiu on routine surgical video recordings - eClinicalMedicine in conversation with - 4 day(s) ago
Andrew Yiu joins Claudia Schafer, Editor-in-Chief for eClinicalMedicine, to talk about his recent paper on adoption of routine surgical video recordings and future implications on policy and clinical practice.Read the full article:https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00124-X/fulltext?dgcid=buzzsprout_icw_podcast_generic_eclinm
Source: eclinicalmedicine.buzzsprout.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 9
These findings underscore the possibility of differential efficacy of medical therapies according to disease distribution. These results warrant further exploration in forthcoming trials to better inform treatment strategies and consideration of disease distribution as a baseline stratification factor in clinical trials.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet-
Differential efficacy of medical therapies for ulcerative colitis according to disease extent: patient-level analysis from multiple RCTs The findings underscore possibility of differential efficacy of medical therapies according to disease distribution https://t.co/I9BbTCVr23 https://t.co/Ar4XQNVUtv
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Mashup Score: 2
Both boosters provided good protection against hospitalisation amongst older adults. The finding that the adjuvanted vaccine targeting the distant Beta strain had similar effectiveness to the bivalent mRNA vaccine targeting more closely matched Omicron sub-lineages is notable and highlights the need for further real-world studies into the effectiveness of vaccines from different vaccine platforms and formulations in the presence of matched and unmatched strains.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 2
The addition of anlotinib to neoadjuvant chemotherapy showed manageable toxicity and encouraging antitumor activity for patients with clinical stage II/III TNBC.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 4Testosterone and the risk of incident atrial fibrillation in older men: further analysis of the ASPREE study - 11 day(s) ago
Circulating testosterone concentrations within the high-normal range are independently associated with an increased risk of incident AF amongst healthy older men. This suggests that AF may be an adverse consequence of high-normal total testosterone concentrations.
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Mashup Score: 3Anti-stigma interventions in low-income and middle-income countries: a systematic review - 13 day(s) ago
The interventions targeted diverse segments of populations and consequently yielded a multitude of stigma-related outcomes. However, despite the heterogeneity of studies, most reported positive outcomes underscoring the effectiveness of existing interventions to reduce stigma.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 3
CD is strongly associated with GORD but there was high heterogeneity. More convincingly, a GFD substantially improves GORD symptoms, suggesting a role for duodenal inflammation and dietary antigens in the aetiology of a subset with GORD. Ruling out CD in patients with GORD may be beneficial.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0
5-year outcomes confirm the findings of the original RAINBOW trial and a planned interim analysis at 2 years, including a reduced frequency of high myopia following ranibizumab treatment. No effects of treatment on non-ocular outcomes were detected.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
CBT for the treatment of #schizophrenia spectrum disorders: an umbrella review of meta-analyses Findings suggest effectiveness of CBT on general and positive symptoms in SSD was small to medium. CBT has no convincing impact on other relevant outcomes. https://t.co/cVzRugCw3c https://t.co/FIRYv3JSXX