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Mashup Score: 1
Acta Pharmacologica Sinica – Ripretinib inhibits HIV-1 transcription through modulation of PI3K-AKT-mTOR
Source: www.nature.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 2COVID-19 and Asthma Onset in Children - 3 day(s) ago
BACKGROUND AND OBJECTIVES:. Respiratory viral infections increase risk of asthma in infants and children. Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can cause severe lung inflammation and prolonged respiratory symptoms. We sought to determine whether SARS-CoV-2 infection modified pediatric incident asthma risk.METHODS:. This retrospective cohort study…
Source: publications.aap.orgCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 1The role and impact of viruses on cancer development - 4 day(s) ago
This review focuses on three major aspects of oncoviruses’ role in cancer development. To begin, we discuss their geographic distribution, revealing that seven oncoviruses cause 20% of all human canc…
Source: onlinelibrary.wiley.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 5
Nature Microbiology – IFITM1 can compete with EBV glycoproteins for EphA2 binding and prevent virus entry into epithelial cells, in vitro and in vivo. YTHDF3 suppresses IFITM1 via the…
Source: www.nature.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 6
Nature Communications – HIV exposed but uninfected infants may face an increased risk of serious infection and mortality. In this work, the authors utilise a cohort from rural Zimbabwe to explore…
Source: www.nature.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 2SARS-CoV-2 nsp15 preferentially degrades AU-rich dsRNA via its dsRNA nickase activity - 9 day(s) ago
Abstract. It has been proposed that coronavirus nsp15 mediates evasion of host cell double-stranded (ds) RNA sensors via its uracil-specific endoribonuclea
Source: academic.oup.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 2Medicine Researcher Spotlight - Lee Quinton, PhD - 10 day(s) ago
Researcher Spotlight for Lee Quinton, PhD
Source: www.umassmed.eduCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 3Myeloid C-type lectin receptors in innate immune recognition - 12 day(s) ago
C-type lectin receptors (CLRs) comprise a vast family of proteins, several of which play key roles in the immune system. In this article, Reis e Sousa et al. review the biology of CLRs expressed by myeloid cells and their role in innate immune responses to infection, commensal organisms, and tissue injury or dysfunction.
Source: www.cell.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 1Enteric coronavirus nsp2 is a virulence determinant that recruits NBR1 for autophagic targeting of TBK1 to diminish the innate immune response - 15 day(s) ago
Non-structural protein 2 (nsp2) exists in all coronaviruses (CoVs), while its primary function in viral pathogenicity, is largely unclear. One such enteric CoV, porcine epidemic diarrhea virus (PED…
Source: www.tandfonline.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 2New drug prevents flu-related inflammation and lung damage - 17 day(s) ago
Findings show a newly created drug can prevent runaway inflammation while still allowing the immune system to handle the virus, even when given late into infection.
Source: www.eurekalert.orgCategories: General Medicine News, Infectious DiseaseTweet
Researchers discovered ripretinib being an LPA candidate, which was ✔️ validated and observed to hinder proviral activation in cell models harboring latent #infections, as well as CD4+ T cells 🧫 derived from infected patients. 🔗 https://t.co/mNsqc4MnM1 https://t.co/2KDB0rf6oc