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Mashup Score: 8Phl p 5 levels more strongly associated than grass pollen counts with allergic respiratory health - 17 day(s) ago
Studies have linked daily pollen counts to respiratory allergic health outcomes, but few have considered allergen levels.We sought to assess associati…
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Mashup Score: 21Neuroimmune interplay during type 2 inflammation: Symptoms, mechanisms, and therapeutic targets in atopic diseases - 23 day(s) ago
Type 2 inflammation is characterized by overexpression and heightened activity of type 2 cytokines, mediators, and cells that drive neuroimmune activa…
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Mashup Score: 14Engineering therapeutic monoclonal antibodies - 2 month(s) ago
The use of human antibodies as biologic therapeutics has revolutionized patient care throughout fields of medicine. As our understanding of the many r…
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Mashup Score: 2Engineering nanoparticle therapeutics for food allergy - 2 month(s) ago
Food allergy is a growing public health issue among children and adults that can lead to life-threatening anaphylaxis following allergen exposure. The…
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Mashup Score: 16Precision engineering for localization, validation, and modification of allergenic epitopes - 2 month(s) ago
The allergen-IgE interaction is essential for the genesis of allergic responses, yet investigation of the molecular basis of these interactions is in …
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Mashup Score: 13The Editors’ Choice - 2 month(s) ago
Treatment options for itch are limited. Antihistamines represent the most widely available class of antipruritic drugs, with over $2 billion in sales per year for itch alone. However, antihistamines exhibit poor efficacy in most chronic itch conditions, even those associated with the histaminergic itch pathway like urticaria. Thus, itch is often classified dichotomously as either histaminergic or nonhistaminergic in nature. In this issue, Trier et al (p 852) provide evidence that suggests that Researchers
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Mashup Score: 2Nasal polyp antibody-secreting cells display proliferation signature in aspirin-exacerbated respiratory disease - 2 month(s) ago
Chronic rhinosinusitis with nasal polyps (CRSwNP) causes nasal obstruction and olfactory dysfunction. Aspirin-exacerbated respiratory disease (AERD) i…
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Mashup Score: 5Genome-wide meta-analysis implicates variation affecting mast cell biology in urticaria - 2 month(s) ago
Urticaria is characterized by inappropriate mast cell degranulation leading to the development of wheals and/or angioedema. Twin and family studies in…
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Mashup Score: 7Single-cell transcriptomics reveals granzyme K–expressing cytotoxic Tfh cells in tertiary lymphoid structures in IgG4-RD - 2 month(s) ago
Germinal center (GC) responses controlled by T follicular helper (Tfh) and T follicular regulatory (Tfr) cells are crucial for the generation of high-…
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Mashup Score: 12Immune responses to SARS-CoV-2 mRNA vaccination in people with idiopathic CD4 lymphopenia - 2 month(s) ago
The immunogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccines is variable in individuals with different inborn erro…
Source: www.sciencedirect.comCategories: General Medicine News, Allergy-ImmunologyTweet
Studies have linked daily pollen counts to respiratory allergic health outcomes, but there is a mismatch between pollen counts and allergen levels. Could daily allergen levels improve risk prediction and help patients better control their symptoms? https://t.co/if8QYLfR0Y