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Mashup Score: 16High-Grade Pleomorphic Sarcomas Treated with Immune Checkpoint Blockade: The MD Anderson Cancer Center Experience - 11 hour(s) ago
Background: Undifferentiated pleomorphic sarcomas (UPSs) are amongst the most common subtypes of soft-tissue sarcomas. Few real-world data on the use of immune checkpoint blockade (ICB) in UPS patients and other high-grade pleomorphic STS patients are available. Purpose: The purpose of our study is to describe the efficacy and toxicity of ICB in patients with advanced UPSs and other high-grade pleomorphic sarcomas treated at our institution. Methods: This is a retrospective, observational study of all patients with metastatic high-grade pleomorphic sarcomas treated with FDA-approved ICB at MD Anderson Cancer Center between 1 January 2015 and 1 January 2023. Patients included in trials for which results are not yet published were excluded. Results: Thirty-six patients with advanced/metastatic pleomorphic sarcomas were included. The median age was 52 years. A total of 26 patients (72%) had UPSs and 10 patients (28%) had other high-grade pleomorphic sarcomas. The median follow-up time was
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Mashup Score: 8How is pain psychology used in cancer care? - 14 hour(s) ago
Psychologist Grace Kao, Ph.D., explains how pain psychology can help patients manage pain caused by cancer symptoms, treatment or side effects.
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Mashup Score: 12Retinoblastoma: 7 insights on this rare eye cancer - 20 hour(s) ago
Retinoblastoma is a rare cancer that forms in the retina and is the most common cancer that starts in the eye in children. Ophthalmologist and retinoblastoma specialist Dan Gombos, M.D., shares what you should know about this rare eye cancer.
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Mashup Score: 6Breast Cancer - 1 day(s) ago
Learn about breast cancer signs, diagnosis, causes, risk factors, and treatment options. Five-year survival rate: 90%. Annual diagnosis: 275,00. Most diagnosis occur: after age 50.
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Mashup Score: 53Dr Kouzy on the Creation of a Centralized Resource to Inform AI Use in Radiation Oncology - 1 day(s) ago
Ramez Kouzy, MD, discusses efforts to improve knowledge of the use of AI in radiation oncology through the creation of an online repository.
Source: www.onclive.comCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 3What is a double mastectomy? - 2 day(s) ago
Rosa Hwang, M.D., answers five questions about double mastectomy, including which patients may benefit from this breast cancer treatment option.
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Mashup Score: 11
Dr. Meagan Krupa came to MD Anderson from Alaska after watching its specialists expertly guide a relative’s local cancer care. Here, she received a corrected diagnosis that changed the course of her breast cancer treatment.
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Mashup Score: 510 cancer symptoms men shouldn't ignore - 2 day(s) ago
Knowing what symptoms to look for can help your doctor find cancer early when it’s most treatable.
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Mashup Score: 4
When Thelma Pollard was diagnosed with an aggressive soft tissue cancer called undifferentiated pleiomorphic sarcoma at age 74, local surgeons recommended hospice care. Instead, she came to MD Anderson and is now cancer-free.
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Mashup Score: 13MD Anderson Research Highlights for May 8, 2024 - 2 day(s) ago
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments at MD Anderson offer insights into expanding the use of FGFR inhibitors, maintaining radiation therapy as standard of care for locally recurrent endometrial cancer, an antibody-drug conjugate for breast cancer, an integrated method of examining protein shapes to optimize drug discovery, a novel CRISPR screening platform to identify functionally redundant genes, a secretory protein target in cancers with chromosome 3q amplifications, optimizing the use of stereotactic radiosurgery for patients with brain metastases, and an evaluation of factors associated with trial enrollment for patients with Non-Hodgkin lymphoma.
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An MD Anderson-led study found improved progression-free survival in patients with pleomorphic sarcomas who received immune checkpoint blockade. Learn about this research: https://t.co/ZAYK5FLt97 @NassifElise @lewisnasr @AJMC_Journal #sarcoma #EndCancer