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Mashup Score: 20
Objective While a substantial body of research describes the disabling impacts of migraine attacks, less research has described the impacts of migraine on physi…
Source: journals.sagepub.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 3Seizures exacerbate excitatory: inhibitory imbalance in Alzheimer’s disease and 5XFAD mice - 22 hour(s) ago
Barbour et al. report that seizures worsen cognitive decline and excitatory:inhibitory imbalance in patients with Alzheimer’s disease. Chronic treatment wi
Source: academic.oup.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 6RAB32 Ser71Arg in autosomal dominant Parkinson's disease: linkage, association, and functional analyses - 5 day(s) ago
RAB32 Ser71Arg is a novel genetic risk factor for Parkinson’s disease, with reduced penetrance. The variant was found in individuals with Parkinson’s disease from multiple ethnic groups, with the same haplotype. In-vitro assays show that RAB32 Arg71 activates LRRK2 kinase, which indicates that genetically distinct causes of familial parkinsonism share the same mechanism. The discovery of RAB32 Ser71Arg also suggests several genetically inherited causes of Parkinson’s disease originated to control intracellular immunity.
Source: www.thelancet.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 18
Background: This study investigates clinical and biomarker differences between standard interval dosing (SID) and extended interval dosing (EID) of ocrelizumab …
Source: journals.sagepub.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 16Genetics of immune response to Epstein-Barr virus: prospects for multiple sclerosis pathogenesis - 5 day(s) ago
Huang et al. examine how a person’s genetic make-up affects their immune response to Epstein-Barr virus and how this relationship affects risk for multiple
Source: academic.oup.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 80Serum GFAP levels correlate with astrocyte reactivity, post-mortem brain atrophy and neurofibrillary tangles - 5 day(s) ago
Sánchez-Juan et al. reveal an association between serum GFAP levels and post-mortem tau pathology in patients with dementia, independent of amyloid deposit
Source: academic.oup.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 44Paraneoplastic Calmodulin Kinase‐Like Vesicle‐Associated Protein (CAMKV) Autoimmune Encephalitis - 5 day(s) ago
Annals of Neurology is a leading neurology journal from the American Neurological Association focusing on diseases of the human nervous system.
Source: onlinelibrary.wiley.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 125Cognitively healthy centenarians are genetically protected against Alzheimer's disease - 8 day(s) ago
BACKGROUND Alzheimer’s disease (AD) prevalence increases with age, yet a small fraction of the population reaches ages > 100 years without cognitive decline. We studied the genetic factors associate…
Categories: General Medicine News, NeurologyTweet
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Mashup Score: 10Racial and ethnic differences in plasma biomarker eligibility for a preclinical Alzheimer's disease trial - 9 day(s) ago
INTRODUCTION In trials of amyloid-lowering drugs for Alzheimer’s disease (AD), differential eligibility may contribute to under-inclusion of racial and ethnic underrepresented groups. We examined pl…
Categories: General Medicine News, NeurologyTweet
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Mashup Score: 2Diversity, equity and inclusion in neurology - 10 day(s) ago
This Series highlights the importance of efforts to improve diversity, equity and inclusion (DEI) in the neurology community and in neurological care to …
Source: www.nature.comCategories: General Medicine News, NeurologyTweet
Physical impairment during and between migraine attacks: A daily diary study of patients with chronic migraine https://t.co/bPJ1Z68G6h