• Mashup Score: 14

    Newsweek spoke to multiple cancer specialists about the concerning rise of cancers among people under 50.

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    • 📰🗞️@Newsweek 🎙️Discussed the troubling rise of #cancer 📈in young adults. Genetics🧬is not responsible for most of the cases. Obesity too doesn’t explain the full picture since a lot of our patients are very active/healthy. ✍️@LucyNotaranton2 🔗https://t.co/WZgEn3mGT3 https://t.co/7kUNcEYCXI

  • Mashup Score: 15

    Immunotherapy is used routinely for treating deficient mismatch repair (dMMR) colon cancer (CC). This case series highlights an emerging safety issue, where patients develop bowel obstruction associated with immunotherapy response.

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    • @MyriamChalabi @OncoAlert @FASinicropeMD ⚠️Also, as we start using more neoadjuvant immunotherapy for MSI-High colon cancers, ☝🏽thing to be mindful of is that responses can be brisk/accelerated. Not uncommon to have this scenario of structure formation; ➡️bowel obstruction. #ASCO25 @OncoAlert https://t.co/YjdR13CMz7 https://t.co/r2cNSD5cgH

  • Mashup Score: 5

    Should biologics be the initial treatment for immune checkpoint inhibitor colitis?

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    • @OncoAlert @mgfakih @isliquidbiopsy @FightCRC @CCAlliance @colontown Important piece @JCO_ASCO that I have found of extreme value in mitigating/stopping🛑immune-related serious adverse events the moment you realize it’s happening. 💉TNFa⛔️ ✅Steroid sparing. 💡Time to adapt. We overuse steroids❌. @OncoAlert #ASCO25 🔗https://t.co/vub6gYA7as https://t.co/lkDvBn5r7b

  • Mashup Score: 57

    Marwan Fakih City of Hope Comprehensive Cancer Center, Duarte, CA Marwan Fakih, Nicholas DeVito, Aparna Parikh, Tanios Bekaii-Saab, Hao Xie, Sandra Algaze, Alexander Spira, J eremy Jones, Cesar Perez, Andrae Vandross, Alberto Bessudo, John Knecht, Ekta Patel, Damiano Fantini, Scott McConnell, Myra Popejoy, Bruce Dezube, Diwakar Davar, Joel Hecht City of Hope Comprehensive Cancer Center, Duarte, CA, Duke University Medical Center, Duke Cancer Institute, Durham, NC, Massachusetts General Hospital, Boston,

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    • #ASCO25👏🏽Encouraging signals as the #immunotherapy story evolves for patients with microsatellite stable (MSS)🧊colorectal cancer. ✅Vilastobart (XTX101)➡️Tumor-activated Fc-enhanced CTLA-4⛔️➕PD-L1⛔️showing deep/durable responses📉 “Cures”. 🔗https://t.co/yroid0g5wO @OncoAlert https://t.co/CVgSXTunHr