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Mashup Score: 107CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity - 11 day(s) ago
CLNS1A promotes autoimmunity through epigenetic and transcriptional regulation of DNA repair and cell cycle progression in CD4 T cells.
Source: www.science.orgCategories: General Medicine NewsTweet
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Mashup Score: 310Noncanonical functions of T follicular helper cells - 13 day(s) ago
We review the roles TFH cells play in regulating immune responses and maintaining homeostasis that extend beyond helping B cell responses.
Source: www.science.orgCategories: General Medicine NewsTweet-
A new Science #Immunology Review examines the multifaceted ways in which T follicular helper cells modulate immune responses during infection, #allergy, and #autoimmune diseases. https://t.co/gdVv4tTbJr https://t.co/0ZqBFdUo0Q
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Mashup Score: 118PSGL-1 is a phagocytosis checkpoint that enables tumor escape from macrophage clearance - 14 day(s) ago
PSGL-1 acts as a phagocytosis checkpoint to promote tumor immune escape through impeding LFA-1 activation in macrophages.
Source: www.science.orgCategories: General Medicine NewsTweet-
A new Science #Immunology study suggests that cancerous cells that express PSGL-1 can escape #phagocytosis by blocking integrin signaling in #macrophages. https://t.co/28MlswX1qB https://t.co/vWXxkgHE6k
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Mashup Score: 295Noncanonical functions of T follicular helper cells - 15 day(s) ago
We review the roles TFH cells play in regulating immune responses and maintaining homeostasis that extend beyond helping B cell responses.
Source: www.science.orgCategories: General Medicine NewsTweet-
A new Science #Immunology Review examines the multifaceted ways in which T follicular helper cells modulate immune responses during infection, #allergy, and #autoimmune diseases. https://t.co/gdVv4tTbJr https://t.co/0ZqBFdUo0Q
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Mashup Score: 100PSGL-1 is a phagocytosis checkpoint that enables tumor escape from macrophage clearance - 18 day(s) ago
PSGL-1 acts as a phagocytosis checkpoint to promote tumor immune escape through impeding LFA-1 activation in macrophages.
Source: www.science.orgCategories: General Medicine NewsTweet-
A new Science #Immunology study suggests that cancerous cells that express PSGL-1 can escape #phagocytosis by blocking integrin signaling in #macrophages. https://t.co/28MlswX1qB https://t.co/vWXxkgHE6k
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Mashup Score: 227Inducible protein degradation reveals inflammation-dependent function of the Treg cell lineage–defining transcription factor Foxp3 - 19 day(s) ago
Acute Foxp3 protein depletion selectively affects Treg cells responding to type 1 inflammation.
Source: www.science.orgCategories: General Medicine NewsTweet-
Scientists have found that the transcription factor FoxP3 performs #inflammation-dependent functions in regulatory T cells (#Tregs) in mouse models of autoimmunity, viral infection, and cancer. @viennabiocenter Read more in Science #Immunology: https://t.co/3oAngXmkbC https://t.co/z0Tr8LRwbF
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Mashup Score: 153
IL-12 is dispensable for CD8 T cell responses to mRNA vaccination, but an Il12 mRNA-LNP enhances CD8 T cell memory and protection.
Source: www.science.orgCategories: General Medicine NewsTweet-
Lipid nanoparticles (LNPs) encoding the cytokine IL-12 can boost CD8 T Cell responses to LNP mRNA #vaccines and improve protection against #SARSCoV2, according to new research in mice. @KingOfPathogens @WeissmanLab Learn more in Science #Immunology: https://t.co/s1GMHCkbnl https://t.co/hNXE4iH1Cp
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Mashup Score: 52Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance - 21 day(s) ago
Refractory PsA patients exhibit dysregulated immunoproteasome and MHC-I machinery, highlighting potential therapeutic targets.
Source: www.science.orgCategories: General Medicine NewsTweet-
Scientists have identified altered gene expression patterns in patients with #psoriatic #arthritis, which could inform new therapeutics for treatment-resistant individuals. @WeizmannScience Read more in Science #Immunology: https://t.co/CtHo0lML9H https://t.co/xrO0LpwAKF
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Mashup Score: 205Inducible protein degradation reveals inflammation-dependent function of the Treg cell lineage–defining transcription factor Foxp3 - 22 day(s) ago
Acute Foxp3 protein depletion selectively affects Treg cells responding to type 1 inflammation.
Source: www.science.orgCategories: General Medicine NewsTweet-
Scientists have found that the transcription factor FoxP3 performs #inflammation-dependent functions in regulatory T cells (#Tregs) in mouse models of autoimmunity, viral infection, and cancer. @viennabiocenter Read more in Science #Immunology: https://t.co/3oAngXmkbC https://t.co/z0Tr8LRwbF
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Mashup Score: 151
IL-12 is dispensable for CD8 T cell responses to mRNA vaccination, but an Il12 mRNA-LNP enhances CD8 T cell memory and protection.
Source: www.science.orgCategories: General Medicine NewsTweet-
Lipid nanoparticles (LNPs) encoding the cytokine IL-12 can boost CD8 T Cell responses to LNP mRNA #vaccines and improve protection against #SARSCoV2, according to new research in mice. @KingOfPathogens @WeissmanLab Learn more in Science #Immunology: https://t.co/s1GMHCkbnl https://t.co/hNXE4iH1Cp
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New research from @Feskelab suggests that chloride nucleotide-sensitive channel 1A (CLNS1A) is a key transcriptional and epigenetic regulator of pathogenic #CD4 #Tcells in mouse models of #autoimmune and inflammatory diseases. https://t.co/Wn6mRdDgvN https://t.co/IdowhYIySG