-
Mashup Score: 39Classification of human chronic inflammatory skin disease based on single-cell immune profiling - 17 hour(s) ago
scRNA-seq of immune cells can distinguish different inflammatory skin diseases and classify indeterminate rashes.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 172Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge - 2 day(s) ago
Human IgG3 with its unique long hinge is a potent activator of intracellular antiviral immunity mediated by TRIM21 and complement.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 51Targeted depletion of PD-1–expressing cells induces immune tolerance through peripheral clonal deletion - 3 day(s) ago
Targeting PD-1+ cells promotes immune tolerance via peripheral clonal deletion of antigen-specific T cells.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 66TIM-3+ CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies - 5 day(s) ago
A subset of CD8 T cells with a terminally exhausted epigenetic profile expressed IFN-γ, granzymes, and perforin in bone marrow.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 114Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis - 6 day(s) ago
Targeting of GALT by anti-α4β7 therapy is associated with therapeutic responses in ulcerative colitis.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 65TIM-3+ CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies - 7 day(s) ago
A subset of CD8 T cells with a terminally exhausted epigenetic profile expressed IFN-γ, granzymes, and perforin in bone marrow.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 80Allogeneic double-negative CAR-T cells inhibit tumor growth without off-tumor toxicities - 8 day(s) ago
Allogeneic CAR-DNTs with minimal genetic modification show potent anti-tumor activity without off-tumor toxicities.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 132
Spatially resolved profiling of the melanoma microenvironment reveals correlates of response to immune checkpoint inhibitors.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 113Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis - 10 day(s) ago
Targeting of GALT by anti-α4β7 therapy is associated with therapeutic responses in ulcerative colitis.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 18Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation - 12 day(s) ago
The transcriptional regulator Trim33 controls Flt3L-driven dendritic cell differentiation.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
Research from 2022 identifies specific patterns of immune cell behavior for diverse skin diseases—such as #AtopicDermatitis and #Psoriasis—and can be used by dermatologists in the clinic. Check out it out: https://t.co/lEDqOTdRPT #WeekendReads https://t.co/zxUot2raFT