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Mashup Score: 16The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication - 1 day(s) ago
Recent or ongoing respiratory inflammation in the lung regulates antiviral immune responses to SARS-CoV-2.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 16The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication - 2 day(s) ago
Recent or ongoing respiratory inflammation in the lung regulates antiviral immune responses to SARS-CoV-2.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research in mice from @mayer_barber suggests that recent or underlying lung inflammation, at the time of #SARSCoV2 infection, pre-activates #InnateImmunity and limits viral replication. Read more in Science #Immunology: https://t.co/dlA5EkLPWZ https://t.co/fAw6VT5jIf
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Mashup Score: 60Contents | Science Immunology 9, 102 - 5 day(s) ago
ONLINE COVER How Helminths Evade the Immune System. Approximately one-third of humans are infected by worm-like parasites called helminths, which have developed multiple strategies to evade immune-mediated destruction. Bohnacker et al. studied mice infected with the murine intestinal helminth Heligmosomoides polygyrus bakeri (Hpb) to define parasite-mediated mechanisms of immune evasion. They report that helminthic glutamate dehydrogenase (heGDH) targets macrophages by inducing production of prostaglandin
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Science #Immunology's December issue is out! This month's cover spotlights how worm-like #parasites called #helminths suppress immune responses and facilitate chronic infections in mice. Read this research and more: https://t.co/jpbopqCZho https://t.co/9s1zOehMgC
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Mashup Score: 47The redox sensor KEAP1 facilitates adaptation of T cells to chronic antigen stimulation by preventing hyperactivation - 9 day(s) ago
KEAP1 promotes persistent T cell immunity and a stem-like T cell response during chronic antigen stimulation by repressing NRF2.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Scientists have identified how the redox sensor #KEAP1 promotes antiviral T cell activation and stem-like T cell responses during chronic viral infections in mice. @utswimmuno @lab_yao Read more in Science #Immunology: https://t.co/AGWrKcxitG https://t.co/i4w4UR2xfq
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Mashup Score: 20A B cell screen against endogenous retroviruses identifies glycan-reactive IgM that recognizes a broad array of enveloped viruses - 12 day(s) ago
Profiling of ERV-reactive B-1 cells in mice reveals natural antibodies against terminal N-acetylglucosamine on multiple viral envelope proteins.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research from @YaleIBIO reveals that natural antibodies secreted by a subset of #Bcells prevent reactivation of endogenous #retroviruses in mice. @VirusesImmunity @YYexin Read more in Science #Immunology: https://t.co/GlSf9GlYh7 https://t.co/n6z4uo1O38
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Mashup Score: 39The redox sensor KEAP1 facilitates adaptation of T cells to chronic antigen stimulation by preventing hyperactivation - 12 day(s) ago
KEAP1 promotes persistent T cell immunity and a stem-like T cell response during chronic antigen stimulation by repressing NRF2.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Scientists have identified how the redox sensor #KEAP1 promotes antiviral T cell activation and stem-like T cell responses during chronic viral infections in mice. @utswimmuno @lab_yao Read more in Science #Immunology: https://t.co/AGWrKcxitG https://t.co/i4w4UR2xfq
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Mashup Score: 31Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction - 13 day(s) ago
Intestinal macrophage LRRK2 kinase activity impairs Paneth cell function in Crohn’s disease.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research suggests that #LRRK2 hyperactivity in intestinal macrophages causes #Paneth cell defects in preclinical models and patients with Crohn’s disease. @washu_pathology Learn more in Science #Immunology: https://t.co/2iwBfg4Z8G https://t.co/uWzRnC8aKU
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Mashup Score: 16A B cell screen against endogenous retroviruses identifies glycan-reactive IgM that recognizes a broad array of enveloped viruses - 14 day(s) ago
Profiling of ERV-reactive B-1 cells in mice reveals natural antibodies against terminal N-acetylglucosamine on multiple viral envelope proteins.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research from @YaleIBIO reveals that natural antibodies secreted by a subset of #Bcells prevent reactivation of endogenous #retroviruses in mice. @VirusesImmunity @YYexin Read more in Science #Immunology: https://t.co/GlSf9GlYh7 https://t.co/n6z4uo1O38
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Mashup Score: 29GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing - 14 day(s) ago
GGNBP2, CNOT10, and CNOT11 are required for innate immune response after the loss of ADAR1-mediated editing of self dsRNA.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New preclinical research suggests that GGNBP2 mediates #autoinflammation triggered by innate immune sensing of self double-stranded RNA in the absence of #ADAR1 activity. @jacki_hf Read more in Science #Immunology: https://t.co/Cf3wSuHwyX https://t.co/NFsjK1q3Ip
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Mashup Score: 31Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction - 15 day(s) ago
Intestinal macrophage LRRK2 kinase activity impairs Paneth cell function in Crohn’s disease.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
New research suggests that #LRRK2 hyperactivity in intestinal macrophages causes #Paneth cell defects in preclinical models and patients with Crohn’s disease. @washu_pathology Learn more in Science #Immunology: https://t.co/2iwBfg4Z8G https://t.co/uWzRnC8aKU
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New research in mice from @mayer_barber suggests that recent or underlying lung inflammation, at the time of #SARSCoV2 infection, pre-activates #InnateImmunity and limits viral replication. Read more in Science #Immunology: https://t.co/dlA5EkLPWZ https://t.co/fAw6VT5jIf