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Mashup Score: 4Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors - 13 hour(s) ago
Cd69 mRNA levels distinguish potent and dysfunctional activation among CD69+ CD8 T cells in tumors.
Source: www.science.orgCategories: General Medicine NewsTweet
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Mashup Score: 84Tuft cells restrain intestinal type 2 immunity through the transcription factor Spi-B - 1 day(s) ago
A tuft cell–centric checkpoint imposed by Spi-B restrains excessive intestinal type 2 immunity and maintains immune homeostasis.
Source: www.science.orgCategories: General Medicine NewsTweet-
Scientists have identified the transcription factor Spi-B to be a checkpoint that restrains excessive #TuftCell-mediated type 2 immunity and food #allergy in mice. @Westlake_Uni @Tsinghua_Uni Learn more in Science #Immunology: https://t.co/vuRZ8fpLM7 https://t.co/gOtzVOqoM7
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Mashup Score: 27Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses - 3 day(s) ago
Co-option of primate-specific retroelements creates an alternative IL-13Rα1 subunit that tunes type 2 immune responses.
Source: www.science.orgCategories: General Medicine NewsTweet-
Scientists have identified an isoform of the Type2 #cytokine receptor subunit IL13Rα1 that can fine tune immune responses and may underlie varied susceptibility to #allergic disease. @TheCrick @imperialcollege Learn more in Science #Immunology: https://t.co/yMwGjEp3gP https://t.co/zdd5yHQcZc
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Mashup Score: 73Tuft cells restrain intestinal type 2 immunity through the transcription factor Spi-B - 4 day(s) ago
A tuft cell–centric checkpoint imposed by Spi-B restrains excessive intestinal type 2 immunity and maintains immune homeostasis.
Source: www.science.orgCategories: General Medicine NewsTweet-
Scientists have identified the transcription factor Spi-B to be a checkpoint that restrains excessive #TuftCell-mediated type 2 immunity and food #allergy in mice. @Westlake_Uni @Tsinghua_Uni Learn more in Science #Immunology: https://t.co/vuRZ8fpLM7 https://t.co/gOtzVOqoM7
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Mashup Score: 26Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses - 5 day(s) ago
Co-option of primate-specific retroelements creates an alternative IL-13Rα1 subunit that tunes type 2 immune responses.
Source: www.science.orgCategories: General Medicine NewsTweet-
Scientists have identified an isoform of the Type2 #cytokine receptor subunit IL13Rα1 that can fine tune immune responses and may underlie varied susceptibility to #allergic disease. @TheCrick @imperialcollege Learn more in Science #Immunology: https://t.co/yMwGjEp3gP https://t.co/zdd5yHQcZc
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Mashup Score: 107CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity - 22 day(s) ago
CLNS1A promotes autoimmunity through epigenetic and transcriptional regulation of DNA repair and cell cycle progression in CD4 T cells.
Source: www.science.orgCategories: General Medicine NewsTweet-
New research from @Feskelab suggests that chloride nucleotide-sensitive channel 1A (CLNS1A) is a key transcriptional and epigenetic regulator of pathogenic #CD4 #Tcells in mouse models of #autoimmune and inflammatory diseases. https://t.co/Wn6mRdDgvN https://t.co/IdowhYIySG
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Mashup Score: 310Noncanonical functions of T follicular helper cells - 24 day(s) ago
We review the roles TFH cells play in regulating immune responses and maintaining homeostasis that extend beyond helping B cell responses.
Source: www.science.orgCategories: General Medicine NewsTweet-
A new Science #Immunology Review examines the multifaceted ways in which T follicular helper cells modulate immune responses during infection, #allergy, and #autoimmune diseases. https://t.co/gdVv4tTbJr https://t.co/0ZqBFdUo0Q
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Mashup Score: 118PSGL-1 is a phagocytosis checkpoint that enables tumor escape from macrophage clearance - 25 day(s) ago
PSGL-1 acts as a phagocytosis checkpoint to promote tumor immune escape through impeding LFA-1 activation in macrophages.
Source: www.science.orgCategories: General Medicine NewsTweet-
A new Science #Immunology study suggests that cancerous cells that express PSGL-1 can escape #phagocytosis by blocking integrin signaling in #macrophages. https://t.co/28MlswX1qB https://t.co/vWXxkgHE6k
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Mashup Score: 295Noncanonical functions of T follicular helper cells - 26 day(s) ago
We review the roles TFH cells play in regulating immune responses and maintaining homeostasis that extend beyond helping B cell responses.
Source: www.science.orgCategories: General Medicine NewsTweet-
A new Science #Immunology Review examines the multifaceted ways in which T follicular helper cells modulate immune responses during infection, #allergy, and #autoimmune diseases. https://t.co/gdVv4tTbJr https://t.co/0ZqBFdUo0Q
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Mashup Score: 100PSGL-1 is a phagocytosis checkpoint that enables tumor escape from macrophage clearance - 29 day(s) ago
PSGL-1 acts as a phagocytosis checkpoint to promote tumor immune escape through impeding LFA-1 activation in macrophages.
Source: www.science.orgCategories: General Medicine NewsTweet-
A new Science #Immunology study suggests that cancerous cells that express PSGL-1 can escape #phagocytosis by blocking integrin signaling in #macrophages. https://t.co/28MlswX1qB https://t.co/vWXxkgHE6k
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Scientists show that paired analysis of #CD69 mRNA and protein levels can help identify potent CD8 T cells with enhanced #cytotoxic effector functions within exhausted populations in tumors. @RayArja @MaxKrummel Learn more in Science #Immunology: https://t.co/rEA3XGLwco https://t.co/7eOsAtBvGg