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Mashup Score: 0
Pangenomes that incorporate many people’s DNA could capture the breadth of human genetic diversity, and quantum computers may be a key enabler.
Source: singularityhub.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0Rat neurons repair mouse brains — and restore sense of smell - 1 day(s) ago
Nature – Scientists develop hybrid mice by filling in missing cells and structures in their brains with rat stem cells.
Source: www.nature.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0
Genome editing with CRISPR RNA-guided endonucleases generates DNA breaks that are resolved by cellular DNA repair machinery. However, analogous methods to manipulate RNA remain unavailable. Here, we show that site-specific RNA breaks generated with type …
Source: www.science.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 2
Transcription initiation is a process that is essential to ensuring the proper function of any gene, yet we still lack a unified understanding of sequence patterns and rules that explain most transcription start sites in the human genome. By predicting …
Source: www.science.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 12
Chronic pain is a multifactorial condition presenting significant diagnostic and prognostic challenges. Biomarkers for the classification and the prediction of chronic pain are therefore critically needed. In this multi-dataset study of over 523,000 participants, we applied machine learning to multi-dimensional biological data from the UK Biobank to identify biomarkers for 35 medical conditions associated with pain (e.g., clinical diagnosis of rheumatoid arthritis, fibromyalgia, stroke, gout, etc.) or self-reported chronic pain (e.g., back pain, knee pain, etc). Biomarkers derived from blood immunoassays, brain and bone imaging, and genetics were effective in predicting medical conditions associated with chronic pain (area under the curve (AUC) 0.62-0.87) but not self-reported pain (AUC 0.50-0.62). Among the biomarkers identified was a composite blood-based signature that predicted the onset of various medical conditions approximately nine years in advance (AUC 0.59-0.72). Notably, all
Source: www.medrxiv.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0AI traces mysterious metastatic cancers to their source - 9 day(s) ago
Nature – Algorithm examines images of metastatic cells to identify the location of the primary tumour.
Source: www.nature.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0
Breaking, a plastic degradation and synthetic biology company, gestated at Colossal Biosciences based on a core discovery out of the Wyss Institute fo
Source: www.businesswire.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0AI traces mysterious metastatic cancers to their source - 9 day(s) ago
Nature – Algorithm examines images of metastatic cells to identify the location of the primary tumour.
Source: www.nature.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0AI traces mysterious metastatic cancers to their source - 10 day(s) ago
Nature – Algorithm examines images of metastatic cells to identify the location of the primary tumour.
Source: www.nature.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology - 10 day(s) ago
Patients hospitalized with COVID-19 exhibit age-dependent immune dysregulation at the transcriptional, protein, and cellular levels.
Source: www.science.orgCategories: General Medicine News, General HCPsTweet
How #QuantumComputers Could Illuminate the Full Range of Human #GeneticDiversity: #Pangenomes https://t.co/pQqYj65Gf8 via @Singularity Hub #genetics #genomics