Information about a real patient is presented in stages (boldface type) to expert clinicians (Drs Michelena and Prakash), who respond to the information and share their reasoning with the reader (regular type). A discussion by the authors follows.Patient presentation: A 24-year-old man, who smoked 1 pack a day of cigarettes, presented to the emergency department with sudden onset of 7/10 chest…
BACKGROUND: The FORZA trial (FFR or OCT Guidance to Revascularize Intermediate Coronary Stenosis Using Angioplasty) prospectively compared the use of fractional flow reserve (FFR) or…
BackgroundBlood pressure (BP) trajectories from young adulthood through middle age are associated with cardiovascular risk. We examined the associations of hypertension risk factors with BP…
BackgroundThe VOYAGER PAD (Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing…
Department of Neurology, The Johns Hopkins School of Medicine, Baltimore, MD. Correspondence to: Elisabeth B. Marsh, MD, Department of Neurology, The Johns Hopkins Hospital, 600…
Negar Asdaghi, MD, MSc Eric D. Goldstein, MD Nastajjia Krementz, MD Dr. Negar Asdaghi: Let’s start with some questions. 1) Is tirofiban a safe replacement…
BackgroundHistorical redlining, a discriminatory lending practice, is an understudied component of the patient risk environment following hospital discharge. We investigated associations between re…
Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, China (J.P.). Department of Cardiology, Shengjing Hospital of China Medical University (T.N.). Yaping…
Bioinformatics and Molecular Genetics at Centenary Institute, The University of Sydney, Sydney, NSW, Australia (Y.C., R.D.B.). Rare Disease and Gene Therapy Division, The Centenary Institute,…
Wildfire smoke (WFS) is a mixture of respirable particulate matter, environmental gases, and other hazardous pollutants that originate from the unplanned burning of arid vegetation…
BackgroundRecently, machine learning algorithms have identified preprocedural γ‐glutamyl transferase (GGT) as a significant predictor of long‐term mortality after coronary revascularization in the …
