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Mashup Score: 7Quality of Life and Bidirectional Gut-Brain Interactions in Irritable Bowel Syndrome From Adolescence to Adulthood - 1 day(s) ago
Reports on cross-sectional and longitudinal associations between health-related quality of life (HRQoL), psychological distress, and irritable bowel syndrome (IBS) in the adolescent and young adult general population are few. We aimed to describe cross-sectional associations between HRQoL and IBS in adolescence and young adulthood, and examine bidirectional gut-brain interactions in the transition from childhood to adulthood.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 4Algorithm Training and Testing for a Nonendoscopic Barrett’s Esophagus Detection Test in Prospective Multicenter Cohorts - 1 day(s) ago
Endoscopic Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC) detection is invasive and expensive. Nonendoscopic BE/EAC detection tools are guideline-endorsed alternatives. We previously described a 5-methylated DNA marker (MDM) panel assayed on encapsulated sponge cell collection device (CCD) specimens. We aimed to train a new algorithm using a 3-MDM panel and test its performance in an independent cohort.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet-
New Publication🎉 @PrasadIyerMD and his team developed a tool to predict the risk of Barrett's esophagus, a possible precursor to esophageal cancer! "Non-endoscopic Barrett's Esophagus detection is critical for improving outcomes of patients with EAC" https://t.co/XTlcK42XQh https://t.co/zu7l8vk6Oa
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Mashup Score: 5Modified-Release Phosphatidylcholine (LT-02) for Ulcerative Colitis: Two Double-Blind, Randomized, Placebo-Controlled Trials - 3 day(s) ago
The aim of this study was to evaluate the efficacy of LT-02, a novel modified-release phosphatidylcholine (PC) formulation, for induction and maintenance of remission in patients with mild to moderate ulcerative colitis (UC) and inadequate response to mesalamine.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 15Alcoholic Foamy Degeneration, an Entity Resembling Alcohol-Associated Hepatitis: Diagnosis, Prognosis, and Molecular Profiling - 5 day(s) ago
Alcoholic foamy degeneration (AFD) is a condition with similar clinical presentation to alcohol-associated hepatitis (AH), but with a specific histologic pattern. Information regarding the prevalence and prognosis of AFD is scarce and there are no tools for a noninvasive diagnosis.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 1Accuracy, Reliability, and Comprehensibility of ChatGPT-Generated Medical Responses for Patients With Nonalcoholic Fatty Liver Disease - 8 day(s) ago
Nonalcoholic fatty liver disease (NAFLD) is an increasing global health problem and is expected to become the leading indication for liver transplantation.1 There are no approved NAFLD-specific pharmacotherapies, and lifestyle modification is the primary recommended therapy.2 Innovative approaches to facilitate the implementation and long-term maintenance of lifestyle changes are needed to address the challenging and complex nature of the management of NAFLD, which recently was renamed as metabolic dysfunction–associated steatotic liver disease, to overcome the limitations and stigma of the previous name.3,4 Artificial intelligence (AI)-powered chatbots have been shown to provide effective personalized support and education to patients, with the potential to complement health care resources. The OpenAI Foundation’s AI chatbot, Chat Generative Pretrained Transformer (ChatGPT), has attracted worldwide attention for its remarkable performance in question–answer tasks.5–7 This study evalua
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 21
A 50-year-old woman presented with right lower-abdominal pain for more than 1 month. Colonoscopy revealed a 1.8-cm submucosal bulge near the appendiceal orifice (Figure A). Computed tomography, magnetic resonance imaging, and endoscopic ultrasound were suspicious for appendiceal mucocele. The patient declined laparoscopic or conventional surgical appendectomy, but agreed to endoscopic transcecal appendectomy (ETA) after multidisciplinary discussion. The procedure steps were as follows (Supplementary Video): the appendiceal lesion margin was marked using a woodpecker I-knife (multifunctional knife, Anrei); a full-thickness circumferential incision was made along the marks and the appendiceal orifice with the woodpecker knife (I- and O-knife); the root of the partially dissected appendix was retracted using a snare to adequately expose the incision line and continue dissection; the woodpecker knife (O-knife) was used to dissect the mesoappendix along the appendix, and mesentery vessels w
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 13Real-World Surgical and Endoscopic Recurrence Based on Risk Profiles and Prophylaxis Utilization in Postoperative Crohn’s Disease - 12 day(s) ago
Preoperative risk stratification may help guide prophylactic biologic utilization for the prevention of postoperative Crohn’s disease (CD) recurrence; however, there are limited data exploring and validating proposed clinical risk factors. We aimed to explore the preoperative clinical risk profiles, quantify individual risk factors, and assess the impact of biologic prophylaxis on postoperative recurrence risk in a real-world cohort.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 335
The purpose of this Clinical Practice Update (CPU) Expert Review is to provide clinicians with guidance on best practices for performing a high-quality upper endoscopic exam.
Source: www.cghjournal.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 6Benefits of Prokinetics, Gastroparesis Diet, or Neuromodulators Alone or in Combination for Symptoms of Gastroparesis - 15 day(s) ago
Prokinetics have limited effectiveness for treating symptoms of gastroparesis. Thus, alternative or adjunct therapies, such as gastroparesis diets or neuromodulators, are often prescribed. Their therapeutic benefits alone or in combination remain unclear.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 5Chronic Liver Disease and Cirrhosis Mortality Rates Are Disproportionately Increasing in Younger Women in the United States Between 2000-2020 - 17 day(s) ago
Previous studies show that mortality from chronic liver disease (CLD) and cirrhosis is increasing in the United States. However, there are limited data on sex-specific mortality trends by age, race, and geographical location. The aim of this study was to conduct a comprehensive time-trend analysis of liver disease–related mortality rates in the National Center of Health Statistics (NCHS) database.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
🔓 Open access article examines the quality of life and bidirectional gut-brain interactions in #IBS from adolescence to adulthood. Learn more at https://t.co/WFw9fTVAEs https://t.co/c4pjzEdo0Z