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Mashup Score: 40Temporal Trends in Body Composition and Metabolic Markers Prior to Diagnosis of Pancreatic Ductal Adenocarcinoma - 23 hour(s) ago
Changes in body composition and metabolic factors may serve as biomarkers for the early detection of pancreatic ductal adenocarcinoma (PDAC). The aim of this study was to capture the longitudinal changes in body composition and metabolic factors prior to diagnosis of PDAC.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 11Misclassified ALD is common in presumed MASLD and highly increases risk for future cirrhosis - 1 day(s) ago
Alcohol overconsumption is a risk factor for disease progression in patients with presumed metabolic dysfunction-associated steatotic liver disease (MASLD). How commonly this occurs and how it affects progression to major adverse liver outcomes (MALO) is not well known.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 18Age, BMI, and Type 2 Diabetes Modify the Relationship Between PNPLA3 and Advanced Fibrosis in Children and Adults With NAFLD - 3 day(s) ago
PNPLA3 G-allele is an important determinant of disease severity in nonalcoholic fatty liver disease (NAFLD). Here, we investigated the effect of age, body mass index (BMI), and type 2 diabetes mellitus (T2DM) on the relationship between PNPLA3 G-allele and advanced fibrosis in adults and children with histologically characterized NAFLD.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 11Screening for Fibrosis Promotes Lifestyle Changes: A Prospective Cohort Study in 4796 Individuals - 6 day(s) ago
Early detection of liver fibrosis is believed to promote lifestyle changes. We evaluated self-reported changes in alcohol intake, diet, exercise, and weight after participating in a screening study for liver fibrosis.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 12
Benefits of computer-aided detection (CADe) in detecting colorectal neoplasia were shown in many randomized trials in which endoscopists’ behavior was strictly controlled. However, the effect of CADe on endoscopists’ performance in less-controlled setting is unclear. This systematic review and meta-analyses were aimed at clarifying benefits and harms of using CADe in real-world colonoscopy.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 19Risk of Major Adverse Cardiovascular Events in Immune-Mediated Inflammatory Disorders on Biologics and Small Molecules: Network Meta-Analysis - 10 day(s) ago
Recent studies raise concern for increased risk of major adverse cardiovascular events (MACE) with Janus kinase (JAK) inhibitors used to treat immune-mediated inflammatory disorders (IMIDs). We aimed to examine MACE risk with licensed biologics and small molecules used commonly between IMIDs: inflammatory bowel disease, rheumatoid arthritis, psoriasis/psoriatic arthritis, and ankylosing spondylitis.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 7Quality of Life and Bidirectional Gut-Brain Interactions in Irritable Bowel Syndrome From Adolescence to Adulthood - 13 day(s) ago
Reports on cross-sectional and longitudinal associations between health-related quality of life (HRQoL), psychological distress, and irritable bowel syndrome (IBS) in the adolescent and young adult general population are few. We aimed to describe cross-sectional associations between HRQoL and IBS in adolescence and young adulthood, and examine bidirectional gut-brain interactions in the transition from childhood to adulthood.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 4Algorithm Training and Testing for a Nonendoscopic Barrett’s Esophagus Detection Test in Prospective Multicenter Cohorts - 13 day(s) ago
Endoscopic Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC) detection is invasive and expensive. Nonendoscopic BE/EAC detection tools are guideline-endorsed alternatives. We previously described a 5-methylated DNA marker (MDM) panel assayed on encapsulated sponge cell collection device (CCD) specimens. We aimed to train a new algorithm using a 3-MDM panel and test its performance in an independent cohort.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 5Modified-Release Phosphatidylcholine (LT-02) for Ulcerative Colitis: Two Double-Blind, Randomized, Placebo-Controlled Trials - 15 day(s) ago
The aim of this study was to evaluate the efficacy of LT-02, a novel modified-release phosphatidylcholine (PC) formulation, for induction and maintenance of remission in patients with mild to moderate ulcerative colitis (UC) and inadequate response to mesalamine.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 15Alcoholic Foamy Degeneration, an Entity Resembling Alcohol-Associated Hepatitis: Diagnosis, Prognosis, and Molecular Profiling - 17 day(s) ago
Alcoholic foamy degeneration (AFD) is a condition with similar clinical presentation to alcohol-associated hepatitis (AH), but with a specific histologic pattern. Information regarding the prevalence and prognosis of AFD is scarce and there are no tools for a noninvasive diagnosis.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
Welcome @YanBiPancDoc to #GITwitter family She is a rock⭐️ #pancreas expert doing really cool research! We share @UMichGIHep roots ➡️@MayoClinicGIHep Check out her newest @AGA_CGH paper https://t.co/dNXMIlLbjH looking at body composition prior to panc cancer diagnosis https://t.co/PKvWY2ubxl