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Mashup Score: 2Exploring Acupuncture's Potential to Mitigate BCG Therapy Side Effects: A Phase I/II Trial - Sarah Psutka - 8 month(s) ago
Zach Klaassen interviews Sarah Psutka about her Phase I/II trial focusing on using acupuncture to mitigate the toxic effects of Bacillus Calmette-Guerin (BCG) therapy for non-muscle invasive bladder cancer. Psutka explains that while BCG is an essential treatment for high-risk cases, it triggers a severe inflammatory response that can lead to an array of symptoms, including urinary urgency,…
Source: www.urotoday.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 1Exploring Acupuncture's Potential to Mitigate BCG Therapy Side Effects: A Phase I/II Trial - Sarah Psutka - 9 month(s) ago
Zach Klaassen interviews Sarah Psutka about her Phase I/II trial focusing on using acupuncture to mitigate the toxic effects of Bacillus Calmette-Guerin (BCG) therapy for non-muscle invasive bladder cancer. Psutka explains that while BCG is an essential treatment for high-risk cases, it triggers a severe inflammatory response that can lead to an array of symptoms, including urinary urgency,…
Source: www.urotoday.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Low-dose or -number of BCG in non-muscle invasive bladder cancer: updated systematic review and meta-analysis | Immunotherapy - 9 month(s) ago
Aim: We aimed to review the evidence of reducing the dose or number of BCG instillations in non-muscle invasive bladder cancer (NMIBC) patients. Material & methods: A literature search was done according to Preferred Reporting Items for Meta-Analyses statement. Results: Overall, 15 and 13 studies were eligible for qualitative and quantitative synthesis, respectively. In patients with NMIBC, lowering either the dose or number of BCG instillations increases the risk of recurrence, but not the risk of progression. Lowering the dose of BCG decreases the risk of adverse events compared with standard-dose BCG. Conclusion: Standard-dose and -number of BCG is preferred for NMIBC patients based on oncologic efficacy; however, low-dose BCG could be considered in selected patients who suffer from significant adverse events.
Source: www.futuremedicine.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 2Exploring Acupuncture's Potential to Mitigate BCG Therapy Side Effects: A Phase I/II Trial - Sarah Psutka - 10 month(s) ago
Zach Klaassen interviews Sarah Psutka about her Phase I/II trial focusing on using acupuncture to mitigate the toxic effects of Bacillus Calmette-Guerin (BCG) therapy for non-muscle invasive bladder cancer. Psutka explains that while BCG is an essential treatment for high-risk cases, it triggers a severe inflammatory response that can lead to an array of symptoms, including urinary urgency,…
Source: UroTodayCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Pembrolizumab combined with CG0070. How can this help patients with NMIBC? Roger Li - 11 month(s) ago
iFrame is not supported! Pembrolizumab combined with CG0070. How can this help patients with NMIBC? Roger Li Roger Li, MD – Genitourinary Oncologist – Moffitt Cancer Center It’s my pleasure to talk to you today about the updated results from the CORE1 trial combining Cretostimogene Grenadorepvec and Pembrolizumab, a…
Source: oncologytube.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
By The ASCO Post Staff Posted: 3/1/2023 10:58:00 AM Last Updated: 3/1/2023 11:20:01 AM Researchers have found that a safe, inexpensive chemotherapy combination may be better tolerated and more effective at preventing high-grade recurrence in patients with non–muscle-invasive bladder cancer than the…
Source: ascopost.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 4
This cohort study compares outcomes of treatment with sequential intravesical gemcitabine and docetaxel vs bacillus Calmette-Guérin among patients with high-risk non–muscle-invasive bladder cancer.
Source: jamanetwork.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 3Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of bladder carcinoma - 1 year(s) ago
The standard of care for most patients with non-muscle-invasive bladder cancer (NMIBC) is immunotherapy with intravesical Bacillus Calmette-GuĂ©rin (BCG), which activates the immune system to recognize and destroy malignant cells and has demonstrated durable clinical benefit. Urologic best-practice guidelines and consensus reports have been developed and strengthened based on data on the timing,…
Categories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1Vaccinia Virus Infection Inhibits Skin Dendritic Cell Migration to the Draining Lymph Node - 1 year(s) ago
Key Points. Replication-competent VACV inhibits skin DC migration to draining lymph node.The VACV-suppressive effect is a general phenomenon of VACV infection i
Categories: Allergy-Immunology, Latest HeadlinesTweet-
#ICYMI from Antonio Rothfuchs @karolinskainst | Using UV-inactivated or modified #VACV #Ankara compared to #BCG vaccination, authors show effects of infection on #skin #DendriticCell migration to the draining #lymphnode | #ReadTheJI #immunology #vaccinia https://t.co/obWswhtiuw https://t.co/OuppIeyVys
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Mashup Score: 0Disseminated BCG disease with defective immune metabolism caused by protein kinase C-delta deficiency - 1 year(s) ago
Protein kinase C-delta encoded by gene PRKCD is a unique member of the protein kinase C family, expressed in all types of tissues, and functions as a key molecule in maintaining immune homeostasis.1 It plays regulatory roles in B-cell signaling, autoimmunity, growth, apoptosis, and differentiation of a variety of cell types.1-3 Since 2013, 17 patients from 10 families have been reported with…
Categories: Allergy-Immunology, Latest HeadlinesTweet
Exciting research on #BladderCancer! Check out this insightful discussion with @spsutkaMD @UW and @zklaassen_md @GACancerCenter exploring the potential of #acupuncture in mitigating side effects of #BCG therapy > https://t.co/XuUfhRYWCh https://t.co/CuvqRBhtoI