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Mashup Score: 1The Auto-Brewery Syndrome: A Perfect Metabolic “Storm” with Clinical and Forensic Implications - 4 day(s) ago
Auto-brewery syndrome (ABS) is a rare, unstudied, unknown, and underreported phenomenon in modern medicine. Patients with this syndrome become inebriated and may suffer the medical and social implications of alcoholism, including arrest for inebriated driving. The pathophysiology of ABS is reportedly due to a fungal type dysbiosis of the gut that ferments some carbohydrates into ethanol and may mimic a food allergy or intolerance. This syndrome should be considered in patients with chronic obstruction or hypomotility presenting with elevated breath and blood alcohol concentrations, especially after a high carbohydrate intake. A glucose challenge test should be performed as the confirmatory test. Treatment typically includes antifungal drugs combined with changes in lifestyle and nutrition. Additional studies are particularly needed on the human microbiome to shed light on how imbalances of commensal bacteria in the gut allow yeast to colonize on a pathological level.
Source: www.mdpi.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 1UMAMI - 24 day(s) ago
Why is the savory flavor umami so delicious?
Categories: General Medicine News, Hem/OncsTweet
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Mashup Score: 2Antibiotics: from prehistory to the present day - 1 month(s) ago
Abstract. Antimicrobials have been in use for many thousands of years in a variety of formats. In this article, I trace how we have moved from ingenious use of
Source: academic.oup.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 454
Histological evidence of tetracycline use has been reported in an ancient X-Group population (350-550 CE) from Sudanese Nubia (Bassett et al., 1980). When bone samples were examined by fluorescent microscopy under UV light at 490 A yellow-green fluorophore deposition bands, similar to those produced …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 88Misuses of “Quality of Life” Judgments in End-of-Life Care - 1 month(s) ago
Physicians’ misperceptions about their disabled patients’ quality of life (QoL) can influence their decision to offer certain medical treatments. There are at least three domains in which misconceptions about a disabled QoL might result in unequal care for disabled patients and could even lead to a patient’s untimely death: (1) futility declarations, (2) recommendations for comfort care, (3) and the distribution of scarce resources. This article argues that medical futility decisions should not be based on a physician’s QoL judgments, that physicians should not steer disabled patients into comfort care when they have treatable illnesses, and that disability alone should never be a reason to deprioritize a patient for scarce medical resources.
Source: journal.chestnet.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 2Professor helps students learn the language of anatomy - 2 month(s) ago
An anatomy professor @OhioStateMed prioritizes connecting with students as they discover the connections of human anatomy.
Source: health.osu.eduCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 16Nebulized vs IV Tranexamic Acid for Hemoptysis - 2 month(s) ago
Nebulized TA may be more efficacious than IV TA in reducing the amount of hemoptysis and need for ED interventional procedures. Future larger studies are needed to further explore the potential of nebulized TA compared with IV TA in patients with mild hemoptysis.
Source: journal.chestnet.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 20
Ingestion of licorice or treatment with chemical derivatives of glycyrrhetinic acid (GA), an active principle of licorice, can cause hypertension, sodium retention, and hypokalemia. Although GA has been shown to inhibit 11 beta-hydroxysteroid dehydrogenase, it may not be the only hepatic enzyme affe …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 23Effect of aldosterone and glycyrrhetinic acid on the protein expression of PAI-1 and p22(phox) in human mononuclear leukocytes - PubMed - 2 month(s) ago
Aldosterone excess can produce heart and kidney fibrosis, which seem to be related to a direct effect of aldosterone at the level of specific receptors. We report a direct, mineralocorticoid-mediated effect on the protein expression of two markers of oxidative stress after incubation of mononuclear …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 26Extract of licorice for the treatment of Addison's disease - PubMed - 2 month(s) ago
Extract of licorice for the treatment of Addison’s disease
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Hem/OncsTweet
Image: https://t.co/IaUpJwVdjG Helpful reference: https://t.co/nA2p77HraN