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Mashup Score: 2High mobility group box 1/Toll-like receptor danger signaling increases brain neuroimmune activation in alcohol dependence - PubMed - 1 hour(s) ago
Ethanol-induced HMGB1/TLR signaling contributes to induction of the proinflammatory cytokine, IL-1β. Increased expression of HMGB1, TLR2, TLR3, and TLR4 in alcoholic brain and in mice treated with ethanol suggests that chronic alcohol-induced brain neuroimmune activation occurs through HMGB1/TLR sig …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
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Mashup Score: 6
Optimizing Renin-Angiotensin System Inhibitor Use in CKD
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, NephrologyTweet
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Mashup Score: 27
Blood Pressure Management in the Patient with Chronic Kidney Disease
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
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Mashup Score: 0Phase 1b clinical trial of ado-trastuzumab emtansine and ribociclib for HER2-positive metastatic breast cancer - PubMed - 8 hour(s) ago
Patients with HER2+ metastatic breast cancer are often treated with a multitude of therapies in the metastatic setting, and additional strategies to prolong responses to anti-HER2 therapies are needed. Preclinical evidence suggests synergy between cyclin-dependent kinase 4 and 6 (CDK 4/6) inhibitors …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
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Mashup Score: 7
anzctr.org.au Identifier: ACTRN12614001294640.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
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Mashup Score: 0"Can I afford to live today?" The emotional toll of navigating the healthcare system with type 1 diabetes - PubMed - 10 hour(s) ago
PWD described strong negative emotions related to navigating the healthcare system and acquiring DMS. Policy changes are urgently needed to support to individuals with type 1 diabetes in order to enhance their quality of life, guarantee equitable access to care, and cultivate a more compassionate an …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
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Mashup Score: 8Cardiac Amyloidosis in Older Adults With a Focus on Frailty: JACC: Advances Expert Consensus - PubMed - 15 hour(s) ago
Amyloidosis, which is caused by misfolded proteins that form amyloid fibrils, is predominantly diagnosed in older adults. Although previously considered a rare disease, increased awareness and noninvasive diagnostic methods have resulted in a rise in diagnoses. As a multisystem disease that affects …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
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Mashup Score: 0Psychotherapy Trends in the United States - PubMed - 1 day(s) ago
Between 2018 and 2021, psychotherapy assumed a larger role in outpatient mental health care while psychotropic medication without psychotherapy, though the modal treatment, became less common. Psychiatrists provided psychotherapy to a decreasing percentage of mental health outpatients, which may hav …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
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Mashup Score: 0
This study found that psychotherapy use increased significantly faster among several socioeconomically advantaged groups and that inequalities were evident in teletherapy access. These trends and patterns highlight a need for clinical interventions and health care policies to broaden access to psych …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
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Mashup Score: 8Cardiac Amyloidosis in Older Adults With a Focus on Frailty: JACC: Advances Expert Consensus - PubMed - 1 day(s) ago
Amyloidosis, which is caused by misfolded proteins that form amyloid fibrils, is predominantly diagnosed in older adults. Although previously considered a rare disease, increased awareness and noninvasive diagnostic methods have resulted in a rise in diagnoses. As a multisystem disease that affects …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
RT @exosome: What better proof do you want that #alcohol induces brain #inflammation ? https://t.co/LeGvo296hN https://t.co/8Ub9X0IBad