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    First-line therapy for advanced non–small-cell lung cancer (NSCLC) that lacks targetable mutations is platinum-based chemotherapy. Among patients with a tumor proportion score for programmed death …

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    • What if you want to see smaller differences? Say, you are already treating patients with some efficacy with current therapies & you want to show that a new regimen is just a bit better? You do a superiority study but you need more patients. https://t.co/AqhSeK0q2P (7/20)

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    ACS CAN is the nation’s leading cancer advocacy organization that is working every day to make cancer issues a national priority.

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    • “If you think research is expensive, try disease…” great quote of #MaryLasker that ⁦@nes047⁩ placed on this ⁦@LinkedIn⁩ posting! Please consider giving to ⁦@ACS_Research⁩’s https://t.co/eohvqE5ZHd https://t.co/eqqd5BJse4

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    Interleukin-10 (IL-10) presents a dual role in systemic lupus erythematosus (SLE), illustrating pro-inflammatory and anti-inflammatory effects. This study addressed the possible associations between serum IL-10 levels and demographic characteristics, laboratory parameters, organ manifestations, disease activity, and treatment response in SLE patients. A total of 88 SLE patients from the Rheumatology Clinic of the Clinical Rehabilitation Hospital, Iași, were enrolled. Disease activity was assessed using the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI). Serum cytokine levels were measured using an enzyme-linked immunosorbent assay (ELISA). Serum IL-10 levels were significantly higher in males compared to females (47.62 pg/mL vs. 13.24 pg/mL, p = 0.011) but not significantly associated with age or disease duration. However, IL-10 showed positive correlations with inflammatory markers and autoantibodies, including C-reactive protein (p = 0.002), IL-6 (p = 0.01), ANA (p = 0.

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    • RT @AutoimmuneList: IL-10 in Systemic Lupus Erythematosus: Balancing Immunoregulation and Autoimmunity #SLE #Lupus https://t.co/isOHZkaXcq

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    Tech billionaires have decided that they should determine our futures for us. According to Elon Musk, Jeff Bezos, Sam Altman, and more, the only good future for humanity is one powered by technology: trillions of humans living in space, functionally immortal, served by superintelligent AIs.  …

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    • Nice & short review of a new book, “More Everything Forever” that critiques some Silicon Valley falsehoods about AI. Caring for humans requires humility & a willingness to help people suffering today. No genie in the AI bottle is coming to save us… https://t.co/6SnRaWruef https://t.co/KsQtjJxcVz

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    Department of Plastic and Reconstructive Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Introduction: Keloids are benign fibroproliferative disorders characterized by excessive collagen deposition and inflammation that extend beyond the original wound boundaries. IL-33 is an alarmin cytokine released upon cellular damage or stress. Dysregulation of IL-33 in epidermal keratinocytes compromises the skin barrier and triggers chronic inflammation.

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    • RT @FrontImmunol: New Research: Keloids and inflammation: the crucial role of IL-33 in epidermal changes https://t.co/9KX6qK6yEv #Frontiers…