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Mashup Score: 0Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity - 10 hour(s) ago
CAR T cells display distinctive profiles and actions in patients with CNS autoimmunity.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 64A lactate-SREBP2 signaling axis drives tolerogenic dendritic cell maturation and promotes cancer progression - 1 day(s) ago
Tumor-derived lactate drives mregDC development and immunotolerant function by activating a SREBP2-dependent transcriptional program.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 113
Carbonyl adducts of nucleobases are MR1-presented self-antigens recognized by T cells.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 75Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity - 5 day(s) ago
CAR T cells display distinctive profiles and actions in patients with CNS autoimmunity.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 62A lactate-SREBP2 signaling axis drives tolerogenic dendritic cell maturation and promotes cancer progression - 5 day(s) ago
Tumor-derived lactate drives mregDC development and immunotolerant function by activating a SREBP2-dependent transcriptional program.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 38Oxidative phosphorylation regulates B cell effector cytokines and promotes inflammation in multiple sclerosis - 7 day(s) ago
OXPHOS-derived ATP and its metabolites modulate the balance of B cell cytokines in health and disease.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 68A TH17-intrinsic IL-1β–STAT5 axis drives steroid resistance in autoimmune neuroinflammation - 7 day(s) ago
IL-1β mediates steroid resistance in TH17 cells via a STAT5-dependent mechanism during autoimmune CNS inflammation.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 117A human model of asthma exacerbation reveals transcriptional programs and cell circuits specific to allergic asthma - 8 day(s) ago
A pathogenic TH2-mononuclear phagocyte-basal cell circuit amplifies mucosal inflammation and drives airway remodeling in asthma.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 129The immunoglobulin superfamily ligand B7H6 subjects T cell responses to NK cell surveillance - 8 day(s) ago
B7H6 protein flags activated T cells for clearance by NK cells, and its genetic deletion enhances T cell proliferation and persistence.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 191
Allergen exposure in wildling mice induces robust de novo responses and activates an endogenous memory TH2 cell pool.
Source: www.science.orgCategories: General Medicine News, Allergy-ImmunologyTweet
#CART cells used to treat #autoimmune neuromyelitis optica spectrum disorder differ from those used to treat #cancer, a new study finds. @HuazhongUST Learn more: https://t.co/N1tvGASOdS https://t.co/9SkZjdetkH