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Mashup Score: 4High-Sensitivity and Conventional Cardiac Troponin-I Assays in AL Amyloidosis - PubMed - 2 day(s) ago
Overall agreement was demonstrated; however, a negative bias for HS-cTnI assay was noted at low concentrations. The application of the conventional cTnI threshold of >100 ng/L to HS-cTnI-based Boston University cardiac staging showed a trend toward downgraded staging assignments. The prognostic u …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 7
Immunoglobulin light chain amyloidosis (AL) is a life-threatening disease caused by the deposition of light chain (LC) and its fragments containing variable (VL) and portions of constant (CL) domains. AL patients feature either monoclonal free LCs (FLCs) circulating as covalent …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Hem/OncsTweet-
Conformational differences in the light chain constant domain of immunoglobulin G and free light chain may influenc… https://t.co/sYGEPm6U97 @BU_Amyloidosis
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Mashup Score: 29
Amyloidosis is a group of complex diseases caused by the misfolding and aggregation of proteins into amyloid fibrils. AL amyloidosis is one of the most prevalent forms of amyloidosis, characterized by the gradual proliferation of light chains from plasma cell clones. A growing body of evidence has c …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Hem/OncsTweet-
Light Chain (AL) Amyloidosis for Nephrologists - Treatment Standard https://t.co/GqutmwPYEX
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Mashup Score: 29
Amyloidosis is a group of complex diseases caused by the misfolding and aggregation of proteins into amyloid fibrils. AL amyloidosis is one of the most prevalent forms of amyloidosis, characterized by the gradual proliferation of light chains from plasma cell clones. A growing body of evidence has c …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Hem/OncsTweet-
Light Chain (AL) Amyloidosis for Nephrologists - Treatment Standard https://t.co/GqutmwPYEX
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Mashup Score: 12Febrile Neutropenia in Patients with Duffy-null Associated Neutrophil Counts and Multiple Myeloma or AL amyloidosis - PubMed - 1 month(s) ago
Febrile Neutropenia in Patients with Duffy-null Associated Neutrophil Counts and Multiple Myeloma or AL amyloidosis
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Hem/OncsTweet-
The unique challenges of managing patients with Duffy-null phenotypes, a crucial aspect of hematologic care. @BU_Amyloidosis Febrile Neutropenia in Patients with Duffy-null Associated Neutrophil Counts and Multiple Myeloma or AL amyloidosis https://t.co/MbnAeCF0sY
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Mashup Score: 22
Published in Amyloid: The Journal of Protein Folding Disorders (Ahead of Print, 2024)
Source: www.tandfonline.comCategories: General Medicine News, Hem/OncsTweet-
dFLC not independently predictive of survival in a uniformly treated patients with bortezomib. Less relevant with more effective treatment with daratumumab. @awechalekar Refining prognostication in systemic AL amyloidosis: limited value of dFLC https://t.co/JadTyTQ4AI
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Mashup Score: 39Defying the Odds: 30 Years in AL Amyloidosis Research, Recent Barriers to Clinical Trial Enrollment - PubMed - 1 month(s) ago
Defying the Odds: 30 Years in AL Amyloidosis Research, Recent Barriers to Clinical Trial Enrollment
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Hem/OncsTweet-
My journey of 30 years in the clinical research field in a rare disease! @BU_Amyloidosis Defying the Odds: 30 Years in AL Amyloidosis Research, Recent Barriers to Clinical Trial Enrollment https://t.co/bZAI2BBrI3
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Mashup Score: 17Machine-learning based subgroups of AL amyloidosis and cumulative incidence of mortality and end stage kidney disease - PubMed - 2 month(s) ago
Immunoglobulin light chain (AL) amyloidosis is a multisystem disease with varied treatment options and disease-related outcomes. Current staging systems rely on a limited number of cardiac, renal, and plasma cell dyscrasia biomarkers. To improve prognostication for all-cause mortality and end-stage …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Hem/OncsTweet-
First clustering algorithm providing survival and ESKD estimates in a large cohort of AL amy @BU_Amyloidosis Machine-learning based subgroups of AL amyloidosis and cumulative incidence of mortality and end stage kidney disea… https://t.co/gSM93yYgH3
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Mashup Score: 17Factors impeding organ recovery despite a deep haematological response in patients with systemic AL amyloidosis - PubMed - 2 month(s) ago
Patients with AL amyloidosis can have persistent organ dysfunction despite achieving a haematological complete response (hemCR). We aimed to identify factors for organ non-response among 143 patients who achieved hemCR for ≥6 months. Kidney, heart and liver non-response were observed in 40/117 (34%) …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Hem/OncsTweet-
Organ response in AL amyloidosis complex, 18-34% organ non-responses despite deep hem CR. @BU_Amyloidosis @a_staron https://t.co/3sBlTb4zFI
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Mashup Score: 2
Myeloma Paper of the Day, September 16th, suggested by Robert Orlowski / AL Amyloidosis, Andrew Staron, cancer, clonal disease, Lisa M. Mendelson, MD Anderson
Source: oncodaily.comCategories: General Medicine News, Hem/OncsTweet-
RT @oncodaily: Myeloma Paper of the Day, September 16th, suggested by @Myeloma_Doc https://t.co/OU8xTKSGTU @a_staron @TracyAJoshi @vsanc…
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High-Sensitivity and Conventional Cardiac Troponin-I Assays in AL Amyloidosis https://t.co/cBEXo9CuPQ @BU_Amyloidosis