• Mashup Score: 2

    Background and Aims The increased frequency of urinary tract infections in patients with primary biliary cholangitis (PBC) and the cross-reactivity between the lipoyl domains (LD) of human pyruvate …

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    • Febrero @HEP_Journal E. coli y la etiología de la #CBP humana: anticuerpos antimitocondriales y determinantes de propagación #LiverTwitter https://t.co/18WVDe4wYe https://t.co/6UPDidB2I1

    • February @HEP_Journal E. coli and the etiology of human PBC: Antimitochondrial antibodies and spreading determinants #LiverTwitter https://t.co/18WVDe4wYe https://t.co/IsRMKmVbFP

  • Mashup Score: 13

    Steady progress over four decades toward understanding the pathogenesis and clinical consequences of hepatic fibrosis has led to the expectation of effective antifibrotic drugs, yet none has been app…

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    • Febrero @HEP_Journal Fibrosis hepática 2022: Necesidades insatisfechas y un plan para el futuro Scott L. #Friedman y Massimo #Pinzani #LiverTwitter https://t.co/pm6OYDw7kx https://t.co/Y7Thjvre5P

    • February @HEP_Journal Hepatic fibrosis 2022: Unmet needs and a blueprint for the future Scott L. #Friedman & Massimo #Pinzani #LiverTwitter https://t.co/pm6OYDNIc5 https://t.co/BUwi5NtYon

  • Mashup Score: 2

    Autoimmune hepatitis (AIH) in pregnancy has many unique considerations. Evidence provided from single centre studies with patient level data and nationwide population studies provide valuable insight…

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    • RT @joaprimo: Autoimmune hepatitis in pregnancy: pearls and pitfalls. @MichaelHenegha8 @HEP_Journal https://t.co/tZDWfqUBbs #livertwitter…

  • Mashup Score: 7

    Background and Aims Cholangiocarcinoma (CCA) is a deadly and highly therapy-refractory cancer of the bile ducts, with early results from immune checkpoint blockade trials showing limited responses. …

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    • #HEP_Highlights Febrero: Carapeto et al identificaron que las células inmunitarias y las moléculas del checkpoint están ⬇️ en el centro del tumor en comparación con el margen invasivo en el CCA TIME. #LiverTwitter https://t.co/p1XrLIS7GH

    • #HEP_Highlights February: Carapeto et al identified that both immune cell and checkpoint molecule expression were ⬇️ in the tumor center compared to the invasive margin in the CCA TIME. A “cold” TIME was associated with poor patient survival. #LiverTwitter https://t.co/p1XrLIS7GH

  • Mashup Score: 3

    Cholangiocarcinoma (CCA) represents the second-most common primary liver malignancy after HCC and has risen in incidence globally in the past decades. Intrahepatic cholangiocarcinoma (iCCA) comprises…

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    • Febrero @HEP_Journal: Trasplante hepático para colangiocarcinoma intrahepático: ¿Listo para el horario estelar? @sapisochin #TommyIvanics @JulieHeimbach #LiverTwitter https://t.co/vNaXifOH3d https://t.co/3BCCywiDMG

    • February @HEP_Journal: Liver Transplantation for Intrahepatic Cholangiocarcinoma: Ready for Prime Time? @sapisochin #TommyIvanics @JulieHeimbach #LiverTwitter https://t.co/vNaXifOH3d https://t.co/4PH2sh6Kjs

  • Mashup Score: 5

    Background and Aims Parenteral nutrition (PN)–associated cholestasis (PNAC) complicates the care of patients with intestinal failure. In PNAC, phytosterol containing PN synergizes with intestinal in…

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    • #HEP_Highlights Febrero: La colestasis asociada a nutrición parenteral (PNAC) es una complicación grave. En un modelo de ratón, Kasmi et al. encontraron que un agonista de FXR disminuyó el daño hepático y la colestasis. #LiverTwitter https://t.co/gqmV9ONr40

    • #HEP_Highlights February: Parenteral nutrition-associated cholestasis (PNAC) is a severe complication. In a mouse model, Kasmi et al. found that an FXR agonist decreased hepatic injury and cholestasis. #LiverTwitter https://t.co/gqmV9OvQcs