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    • Mashup Score: 0
      Intermediate-risk Non-muscle-invasive Bladder Cancer: Updated Consensus Definition and Management Recommendations from the International Bladder Cancer Group - PubMed - 2 year(s) ago

      Standardizing the definition of intermediate-risk (IR) non-muscle-invasive bladder cancer (NMIBC), which is a heterogeneous disease, is critical for appropriate management of patients. The International Bladder Cancer Group recommends classification of IR NMIBC tumors and personalized management bas …

      Source: PubMed
      Categories: Dental, Latest Headlines, Onc News and Journals
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      • Profile photo of 	kgiacomini
        kgiacomini

        Thoughts

    • Mashup Score: 0
      Intermediate-risk Non-muscle-invasive Bladder Cancer: Updated Consensus Definition and Management Recommendations from the International Bladder Cancer Group - PubMed - 2 year(s) ago

      Standardizing the definition of intermediate-risk (IR) non-muscle-invasive bladder cancer (NMIBC), which is a heterogeneous disease, is critical for appropriate management of patients. The International Bladder Cancer Group recommends classification of IR NMIBC tumors and personalized management bas …

      Source: PubMed
      Categories: Dental, Latest Headlines, Onc News and Journals
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      • Profile photo of 	kgiacomini
        kgiacomini

        Pubmed

    • Mashup Score: 3
      Efficacy of melphalan and prednisone plus thalidomide in patients older than 75 years with newly diagnosed multiple myeloma: IFM 01/01 trial - PubMed - 2 year(s) ago

      This trial confirms the superiority of the combination melphalan and prednisone plus thalidomide over melphalan and prednisone alone for prolonging survival in very elderly patients with newly diagnosed myeloma. Toxicity was acceptable.

      Source: PubMed
      Categories: Latest Headlines, Partners & KOLs
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      • Profile photo of 	ManniMD1
        ManniMD1

        A trip down memory lane- and another great trial by the IFM group. IFM 01/01 (enrolled from 2002-06) Melphalan/pred (MP) vs MP+thalidomide (MPT) in patients aged ≥75 with MM Primary Endpoint: Overall Survival, 29 mo for MP vs 44 mo for MPT #mmsm https://t.co/PhBfc1DgBZ https://t.co/DVm2gdT1ZK

    • Mashup Score: 4
      Safety and clinical activity of autologous RNA chimeric antigen receptor T-cell therapy in myasthenia gravis (MG-001): a prospective, multicentre, open-label, non-randomised phase 1b/2a study - PubMed - 2 year(s) ago

      Cartesian Therapeutics and National Institute of Neurological Disorders and Stroke of the National Institutes of Health.

      Source: PubMed
      Categories: Hem/Oncs, Latest Headlines
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      • Profile photo of 	drkomanduri
        drkomanduri

        Congrats to Volkan Granit and entire study team. Safety and clinical activity of autologous RNA chimeric antigen receptor T-cell therapy in myasthenia gravis (MG-001): a prospective, multicentre, open-label, non-randomised phase 1b/2a study. #BCMA #tcellrx https://t.co/2reiazDC8h

    • Mashup Score: 0
      Dietary Choline Supplements, but Not Eggs, Raise Fasting TMAO Levels in Participants with Normal Renal Function: A Randomized Clinical Trial - PubMed - 2 year(s) ago

      Despite high choline content in egg yolks, healthy participants consuming 4 eggs daily showed no significant increase in TMAO or platelet reactivity. However, choline bitartrate supplements providing comparable total choline raised both TMAO and platelet reactivity, demonstrating that the form and s …

      Source: PubMed
      Categories: Latest Headlines, Partners & KOLs
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      • Profile photo of 	drjkahn
        drjkahn

        Interesting. Science is science. Dietary Choline Supplements, but Not Eggs, Raise Fasting TMAO Levels in Participants with Normal Renal Function: A … https://t.co/GkE5bHWlxl @megynkelly

    • Mashup Score: 7
      Financial Toxicity in Oncology, More Unanswered Questions - PubMed - 2 year(s) ago

      Financial Toxicity in Oncology, More Unanswered Questions

      Source: PubMed
      Categories: Latest Headlines, Partners & KOLs
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      • Profile photo of 	ManniMD1
        ManniMD1

        "An integral part of improving value is less reliance on unvalidated surrogate end points and recognition that these end points can mislead and often inherently predispose to more therapy and as a result more financial toxicity" @RBeechPharmD @kczmj https://t.co/z652dNrq2S https://t.co/29E8BZhAOm

    • Mashup Score: 1
      Randomized comparison of cooked and noncooked diets in patients undergoing remission induction therapy for acute myeloid leukemia - PubMed - 2 year(s) ago

      In patients treated in a PE, a neutropenic diet did not prevent major infection or death.

      Source: PubMed
      Categories: Hem/Oncs, Latest Headlines
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      • Profile photo of 	mtmdphd
        mtmdphd

        RCT cooked & noncooked (neutropenic) diets in Pts undergoing remission AML Tx [2008] Gardner et al. @JCO_@ASCO https://t.co/mlAkx4Vowy #SuppOnc #IDonc #leusm #AMLsm

    • Mashup Score: 0
      Early Management of Paediatric Wrist and Forearm Fractures in a Busy District General Hospital Emergency Department: A Retrospective Cohort Comparison Study and Audit of BOAST Guidelines - PubMed - 2 year(s) ago

      Implementation of the Trust pathway in accordance with the BOAST guidelines along with staff education has standardized the practice at our Trust. It saved approximately 63 hours of trauma theatre time for the six-month data collection period. Our findings also suggest that this has favourable outco …

      Source: PubMed
      Categories: Latest Headlines, Orthopedics
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      • Profile photo of 	BritOrthopaedic
        BritOrthopaedic

        New research shows that our BOAST guidelines for the early management of distal forearm fractures in children saved approximately 63 hours of trauma theatre time over six months. Read the full report here: https://t.co/AojxAGCy9x https://t.co/xkkoNAIHo2

    • Mashup Score: 1
      Combination of ciprofloxacin/celecoxib as a novel therapeutic strategy for ALS - PubMed - 2 year(s) ago

      This study supports the safety and tolerability of PrimeC in ALS. Biomarker analyses suggest early evidence of a biological effect. A placebo-controlled trial is required to disentangle the biomarker results from natural progression and to evaluate the efficacy of PrimeC for the treatment of ALS. Su …

      Source: PubMed
      Categories: Latest Headlines, Rare Disease
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      • Profile photo of 	alsadvocacy
        alsadvocacy

        RT @rpavaneijk: @onein300 @Jeanc9orf72 @alsadvocacy Yes exactly, I really like the approach in this trial: https://t.co/8hUmvsry93. They at…

    • Mashup Score: 2
      Effect of proprotein convertase subtilisin/kexin type 9 inhibition on cancer events: A pooled, post hoc, competing risk analysis of alirocumab clinical trials - PubMed - 2 year(s) ago

      Intensive low-density lipoprotein cholesterol lowering with a proprotein convertase subtilisin/kexin type 9 inhibitor combined with statin does not appear to increase the risk of new or worsening cancer events.

      Source: PubMed
      Categories: Cardiologists, Latest Headlines
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      • Profile photo of 	Hragy
        Hragy

        RT @Drlipid: PCSK9i showing no cancer risk - see https://t.co/6EIAJp9Ayy

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