-
Mashup Score: 1Natalizumab administration in multiple sclerosis patients during active SARS-CoV-2 infection: a case series - BMC Neurology - 2 year(s) ago
Background The Coronavirus disease 2019 (COVID-19) caused by the new Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has become a pandemic, affecting the therapeutic management for Multiple Sclerosis (MS). Any decision regarding the discontinuation of high-potency agents for moderate and highly active MS should be carefully evaluated, taking into account the potential risk of rebound…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
-
Mashup Score: 1Longitudinal observational study of boxing therapy in Parkinson’s disease, including adverse impacts of the COVID-19 lockdown - BMC Neurology - 3 year(s) ago
Background Parkinson’s Disease (PD) is a highly prevalent neurodegenerative disease whose incidence is increasing with an aging population. One of the most serious manifestations of PD is gait instability, leading to falls and subsequent complications that can be debilitating, even fatal. Boxing therapy (BT) uses gait and balance exercises to improve ambulation in people with PD, though its…
Source: BMC NeurologyCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
-
Mashup Score: 0Longitudinal observational study of boxing therapy in Parkinson’s disease, including adverse impacts of the COVID-19 lockdown - BMC Neurology - 3 year(s) ago
Background Parkinson’s Disease (PD) is a highly prevalent neurodegenerative disease whose incidence is increasing with an aging population. One of the most serious manifestations of PD is gait instability, leading to falls and subsequent complications that can be debilitating, even fatal. Boxing therapy (BT) uses gait and balance exercises to improve ambulation in people with PD, though its…
Source: BMC NeurologyCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
-
Mashup Score: 1
Background The purpose of this study was to describe the effects of COVID-19 social distancing on the function, health, and well-being of people with Parkinson disease (PD), and test the association of these effects with patients’ activation levels, i.e., their skills and confidence in managing their health. Methods Community-dwelling individuals with PD answered an anonymous web-based survey….
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
-
Mashup Score: 0National registry for amyotrophic lateral sclerosis: a systematic review for structuring population registries of motor neuron diseases - 3 year(s) ago
Background This article comprises a systematic review of the literature that aims at researching and analyzing the frequently applied guidelines for structuring national databases of epidemiological surveillance for motor neuron diseases, especially Amyotrophic Lateral Sclerosis (ALS). Methods We searched for articles published from January 2015 to September 2019 on online databases as PubMed -…
Source: BMC NeurologyCategories: Latest Headlines, Rare DiseaseTweet
-
Mashup Score: 0Increased cerebrospinal fluid adenosine 5'-triphosphate in patients with amyotrophic lateral sclerosis - 3 year(s) ago
Background Extracellular adenosine 5′-triphosphate (ATP) has been suggested to cause neuroinflammation and motor neuron degeneration by activating microglia and astrocytes in amyotrophic lateral sclerosis (ALS). Since we have developed a highly sensitive ATP assay system, we examined cerebrospinal fluid (CSF) ATP levels in patients with ALS whether it can be a useful biomarker in ALS. Methods…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
-
Mashup Score: 1Case report of homozygous E200D mutation of PRNP in apparently sporadic Creutzfeldt-Jakob disease - 3 year(s) ago
Background Inherited prion diseases are rare autosomal dominant disorders associated with diverse clinical presentations. All are associated with mutation of the gene that encodes prion protein (PRNP). Homozygous mutations with atypical clinical phenotypes have been described but are extremely rare. Case presentation A Chinese patient presented with a rapidly progressive cognitive and motor…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
-
Mashup Score: 0Increase of blood-brain barrier leakage is related to cognitive decline in vascular mild cognitive impairment - 3 year(s) ago
Background Blood-brain barrier (BBB) breakdown, as an early biomarker for vascular mild cognitive impairment (vMCI), has only been validated by a few studies. The aim of this study was to investigate whether compromised BBB integrity is involved in vMCI patients, and detect the relationship between BBB breakdown and cognitive function. BBB leakage in vMCI was explored, and the relationship…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
-
Mashup Score: 0
Backgrounds The reports of neurological symptoms are increasing in cases with coronavirus disease 2019 (COVID-19). This multi-center prospective study was conducted to determine the incidence of neurological manifestations in hospitalized cases with COVID-19 and assess these symptoms as the predictors of severity and death. Methods Hospitalized males and females with COVID-19 who aged over…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
-
Mashup Score: 1The relationship between consciousness and the ascending reticular activating system in patients with traumatic brain injury - 4 year(s) ago
We investigated the relationship between consciousness and the ascending reticular activating system (ARAS) by using diffusion tensor tractography (DTT) in patients with traumatic brain injury (TBI). Twenty-six patients with TBI and 13 healthy control subjects were recruited for this study. Glasgow Coma Scale (GCS) scores were used for evaluation of subject consciousness state at the chronic…
Source: BMC NeurologyCategories: Latest Headlines, NeurologyTweet
Natalizumab administration in multiple sclerosis patients during active SARS-CoV-2 infection: a case series https://t.co/sYeSAn9B0V