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Mashup Score: 107Detection of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in New York City | Journal of Virology - 14 hour(s) ago
While surveillance programs for avian influenza viruses are often focused on migratory routes and their associated stop-over locations or commercial poultry operations, many bird species—including migratory birds—frequent or live in urban green spaces and …
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Mashup Score: 6
In this work, we designed a vaccine with a cluster of multiple T-cell/B-cell epitopes, which should be effective in inducing systematic immune responses against variola virus infection. Besides, this work also provides a reference in vaccine design for …
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Mashup Score: 9Research Funding: the Case for a Modified Lottery | mBio - 9 day(s) ago
ABSTRACT The time-honored mechanism of allocating funds based on ranking of proposals by scientific peer review is no longer effective, because review panels cannot accurately stratify proposals to identify the most meritorious ones. Bias has a major …
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Mashup Score: 5
We investigated the capacity of intravenous immunoglobulins manufactured previously over two decades (1998–2020) to neutralize or enhance Zika virus infection in vitro. West Nile virus antibodies in IGIVs could not neutralize Zika virus initially; however,…
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Mashup Score: 0Indirect CD4+ T cell protection against mouse gamma-herpesvirus infection via interferon gamma | Journal of Virology - 18 day(s) ago
CD4+ T cells are critical for the control of gamma-herpesvirus infection; they act indirectly, by recruiting natural killer (NK) cells to attack infected target cells. Here, we report that the CD4+ T cell/NK cell axis of gamma-herpesvirus control requires …
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Mashup Score: 8Outpatient treatment with concomitant vaccine-boosted convalescent plasma for patients with immunosuppression and COVID-19 | mBio - 27 day(s) ago
As SARS-CoV-2 evolves, new variants of concern (VOCs) have emerged that evade available anti-spike monoclonal antibodies, particularly among immunosuppressed patients. However, high-titer COVID-19 convalescent plasma continues to be effective against VOCs …
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Mashup Score: 1Intestinal capillariasis | Clinical Microbiology Reviews - 27 day(s) ago
Intestinal capillariasis caused by Capillaria philippinensis appeared first in the Philippines and subsequently in Thailand, Japan, Iran, Egypt, and Taiwan, but most infections occur in the Philippines and Thailand. As established experimentally, the life …
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Mashup Score: 24A ketogenic diet enhances fluconazole efficacy in murine models of systemic fungal infection | mBio - 1 month(s) ago
Invasive fungal infections cause over 2.5 million deaths per year around the world. Treatments for fungal infections are limited, and there is a significant need to develop strategies to enhance antifungal efficacy, combat antifungal resistance, and …
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Mashup Score: 7Burkholderia cepacia Complex Bacteria: a Feared Contamination Risk in Water-Based Pharmaceutical Products | Clinical Microbiology Reviews - 1 month(s) ago
Burkholderia cepacia (formerly Pseudomonas cepacia) was once thought to be a single bacterial species but has expanded to the Burkholderia cepacia complex (Bcc), comprising 24 closely related opportunistic pathogenic species. These bacteria have a …
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Mashup Score: 21Cutaneous Mycobacterial Infections | Clinical Microbiology Reviews - 2 month(s) ago
Humans encounter mycobacterial species due to their ubiquity in different environmental niches. In many individuals, pathogenic mycobacterial species may breach our first-line barrier defenses of the innate immune system and modulate the activation of …
Source: journals.asm.orgCategories: General Medicine News, Hem/OncsTweet
Not very surprising, as H5N1 is everywhere in birds & birds can fly. But response depends on finding them, which depends on looking. This great new piece from Randy Albrecht, @florian_krammer, @CMarizzi et al shows that community scientists can help look. https://t.co/lcvUvhkQTJ