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Mashup Score: 1Evaluating the Impact of Metastatic Breast Cancer on Patients - 3 hour(s) ago
An expert panel discusses the clinical and economic impact of metastatic breast cancer (mBC) on patients, the prognosis for those with mBC, the three FDA-approved CDK4/6 inhibitors for HR+/HER2- mBC, and the importance of overall survival as a clinical trial endpoint and its relevance to clinical practice.
Source: www.pharmacytimes.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 0Annals of Internal Medicine: Latest - 4 hour(s) ago
Can’t sign in? Forgot your password? If the address matches an existing account you will receive an email with instructions to reset your password. Can’t sign in? Forgot your username? Laurence Duquenne, MD, Elizabeth M. Hensor, PhD, Michelle Wilson, MSc, Leticia Garcia-Montoya, MD, Jacqueline L. Nam, MBBCh, FCP (SA), Cert Rheum (SA), PhD, Jianhua Wu, PhD, Kate Harnden, MBChB, Innocent Chidi Anioke, MSc, Andrea Di Matteo, PhD, Rahaymin Chowdhury, MBChD, MD, Navkiran Sidhu, MD, Frederique Ponchel, PhD,
Source: www.acpjournals.orgCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 1eBioMedicine, October 2023, Volume 96 - 5 hour(s) ago
Read the current issue of The Lancet Microbe, providing a destination for the best microbiology-focused clinical research
Source: www.thelancet.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 0What We’re Reading: Merck Halts Skin Cancer Trial; GLP-1 Drug Usage in the US; Psychedelic Therapy Gains Momentum - 7 hour(s) ago
Challenges in developing next-generation cancer therapies persist; research indicates widespread utilization and hurdles in affordability and access to glucagon-like peptide-1 (GLP-1) medications; legislation seeks to legalize therapeutic use of psychedelics in California.
Source: www.ajmc.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 0
A provisional determination is also provided for the 40 mg/0.4 mL strength due to remaining interchangeability designation for another biosimilar to Humira.
Source: www.pharmacytimes.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 6The histone lysine methyltransferase MLL1 regulates the activation and functional specialization of regulatory TÂ cells - 7 hour(s) ago
Wang et al. explore the functional role of MLL1 in mouse Tregs. They demonstrate that MLL1 is not required for the thymic development of Tregs but plays a vital role in immune self-tolerance by creating an appropriate epigenetic context for Treg activation and functional specialization.
Source: www.cell.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 6
Menopause marks a significant transition for women, yet understanding its precursor, perimenopause, and its symptoms can be complex. Dr. Stephanie […]
Source: newsnetwork.mayoclinic.orgCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 1
In this episode of Annals On Call, Dr. Centor discusses the current increase in cases of dengue with Drs. Davidson Hamer and Ralph Huits.
Source: www.acpjournals.orgCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 2Develop Strategies for Managing Medications During Sick Days - 9 hour(s) ago
Strategies for intervention design focused on opportunities for both patients and providers by way of medication labeling, specific prescription instructions, prescribing prompts, and educational services.
Source: www.pharmacytimes.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 0Exploring the ageing methylome in the model insect, Nasonia vitripennis - BMC Genomics - 11 hour(s) ago
Background The ageing process is a multifaceted phenomenon marked by the gradual deterioration of cellular and organismal functions, accompanied by an elevated susceptibility to diseases. The intricate interplay between genetic and environmental factors complicates research, particularly in complex mammalian models. In this context, simple invertebrate organisms have been pivotal, but the current models lack detectable DNA methylation limiting the exploration of this critical epigenetic ageing mechanism. This study introduces Nasonia vitripennis, the jewel wasp, as an innovative invertebrate model for investigating the epigenetics of ageing. Leveraging its advantages as a model organism and possessing a functional DNA methylation system, Nasonia emerges as a valuable addition to ageing research. Results Whole-genome bisulfite sequencing unveiled dynamic alterations in DNA methylation, with differentially methylated CpGs between distinct time points in both male and female wasps. These
Source: bmcgenomics.biomedcentral.comCategories: General Medicine News, General Journals & SocietTweet
Join us to discuss the clinical impact of mBC, FDA-approved CDK4/6 inhibitors in personalized treatment, evaluating medication toxicity profiles, and more! Gain expert perspectives in the must-watch Peer Exchange episodes. Tune in here: https://t.co/wRA8UXgFZx. https://t.co/E1kLfWAdVa